Serum prolactin and CA 125 levels in uterine adenomyosis

被引:1
|
作者
Yorganci, Aycag [1 ]
Kadioglu, Nezaket [2 ]
Gumgumcu, Harika [1 ]
Ozyer, Sebnem [1 ]
Engin-Ustun, Yaprak [3 ]
机构
[1] Ankara City Hosp, Dept Ob&Gyn, Minist Hlth, Univ Mahallesi 1604,Cadde 9, TR-06800 Ankara, Turkey
[2] Ankara Liv Hosp, Ankara, Turkey
[3] Etlik Zubeyde Hanim Womens Hlth Educ & Res Hosp, Ankara, Turkey
关键词
Uterine adenomyosis; uterine volume; prolactin; cancer antigen 125; miscarriage; UTERUS; DIAGNOSIS;
D O I
10.1177/2284026520946207
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: It is suggested that prolactin has a role in the pathogenesis of uterine adenomyosis. Besides, it is also reported that elevated cancer antigen 125 levels are related with this benign disorder. The aim of the study was to investigate serum prolactin and cancer antigen 125 levels in patients with adenomyosis. Methods: In this retrospective chart review study, data of patients with clinically diagnosed and histopathologically proven adenomyosis in hysterectomy specimens were analyzed. Patients were divided into two groups according to the ultrasonographically calculated preoperative uterine volume: Group 1 (n = 62): uterine volume <= 240 cm(3)(<= 12 gestational weeks) and Group 2 (n = 42): uterine volume >240 cm(3)(>12 gestational weeks). Age, obstetric history, body mass index, preoperative hemoglobin, thyroid stimulating hormone, prolactin and cancer antigen 125 levels, and ultrasonographic findings were recorded. Preoperative prolactin and cancer antigen 125 values were compared between the two groups. Results: A total of 104 patients were included in the study. No differences in the baseline characteristics were observed between the groups, except the number of pregnancies and miscarriages. Furthermore, no significant differences were observed in terms of serum prolactin and cancer antigen 125 levels between the groups. Conclusion: Serum prolactin and cancer antigen 125 levels were not associated with uterine volume in patients with uterine adenomyosis.
引用
收藏
页码:165 / 169
页数:5
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