Oncofertility: a new focus in women health-care ...

被引:8
|
作者
Chevalier, N. [1 ]
Dewailly, Didier [2 ]
Fenichel, Patrick [1 ]
机构
[1] Hop Archet 1, CECOS, Serv Endocrinol & Med Reprod, F-06202 Nice 3, France
[2] Hop Jeanne Flandre, Serv Gynecol Endocrinienne & Med Reprod, F-59037 Lille, France
关键词
fertility preservation; oncofertility; in vitro oocyte maturation; premature ovarian failure; cryopreservation; cancer; CRYOPRESERVED OVARIAN TISSUE; BREAST-CANCER PATIENTS; DEVELOPMENT IN-VITRO; FERTILITY PRESERVATION; HUMAN OOCYTES; MEIOTIC SPINDLE; CULTURE-SYSTEM; TRANSPLANTATION; FOLLICLES; PREGNANCY;
D O I
10.1016/S0003-4266(09)72474-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although treatment and survival are the primary focus of health-care patients, with cancer survivors living longer it is now appropriate to consider their quality of life after treatment, including the possibility of becoming parents. There are several options for fertility preservation in cancer patients. Even though most of them are still experimental and their efficacy and reliability have not been determined, especially in women. The most successful alternative for female Survivors is embryo cryopreservation, an approach not suitable for many single or virgin women or even possible for prepubertal girls. Reports of live birth after transplantation of human ovarian tissue have reinforced the clinical potential of ovarian tissue banking for fertility preservation. Many exciting Studies are underway to improve the efficacy and solve the problems With Current fertility preservation strategies, especially for in vitro Culture of cryopreserved tissue or follicles. Continuous efforts to improve Current strategies and to develop new strategies will benefit many women and children who are facing premature ovarian failure and sterility. (C) 2009 Elsevier Masson SAS. All rights reserved
引用
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页码:S33 / S41
页数:9
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