Tolerance to the glycopeptides vancomycin and teicoplanin in coagulase-negative staphylococci

被引：33

作者：

Bourgeois, Ingrid

Pestel-Caron, Martine

Lemeland, Jean-Francois

Pons, Jean-Louis

Caron, Francois

机构：

[1] Univ Rouen, UFR Med Pharm, Grp Rech Antimicrobiens & Microorgan, UPRES EA 2656,IFR 23, F-76183 Rouen, France

[2] Ctr Hosp Univ, F-76031 Rouen, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 02期

关键词：

D O I：

10.1128/AAC.00719-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Tolerance to vancomycin and teicoplanin in 90 clinical isolates of coagulase-negative staphylococci (CoNS) was investigated by time-kill curve methodology. Only six strains, belonging to the Staphylococcus lugdunensis species, exhibited tolerance. The seven other S. lugdunensis strains tested displayed weak susceptibility to the bactericidal activity of glycopeptides compared to the other CoNS. These phenomena are of concern, since S. lugdunensis is recognized as one of the most pathogenic CoNS.

引用

页码：740 / 743

页数：4

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