Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review

被引：8
|
作者：
Chen, Dawei [1 ,2 ]
Zhang, Yan [2 ]
Shi, Fang [2 ]
Li, Minghuan [2 ]
Zhu, Hui [2 ]
Kong, Li [2 ]
Yu, Jinming [2 ]
机构：
[1] Weifang Med Univ, Weifang, Peoples R China
[2] Shandong Canc Hosp & Inst, Dept Radiat Oncol, Jinan 250117, Shandong, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2015年 / 8卷
关键词：
bevacizumab; lung cancer; malignant pericardial effusion; ENDOTHELIAL GROWTH-FACTOR; PLEURAL EFFUSIONS; CISPLATIN; ASCITES;
D O I：
10.2147/OTT.S90145
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Malignant pericardial effusion (MPCE) is a common complication of advanced malignant tumors, and interferes severely with patient prognosis and quality of life. The standard treatment for this complication is intracavitary perfusion of chemotherapeutic drugs, which is limited by unsatisfactory therapeutic effects and serious adverse events. We report a patient with MPCE who was treated with bevacizumab by pericardial perfusion, resulting in a complete response. This case supports the use of intrapericardial bevacizumab as a potential treatment for MPCE.
引用
收藏
页码：2767 / 2770
页数：4
相关论文
共 50 条
  • [1] Intrapericardial bevacizumab safely and effectively treats malignant pericardial effusion in advanced cancer patients
    Chen Dawei
    Zhang Yan
    Shi Fang
    Zhu Hui
    Li Minghuan
    Chen Kaijun
    Kong Li
    Yu Jinming
    ONCOTARGET, 2016, 7 (32) : 52436 - 52441
  • [2] A case of advanced lung cancer with malignant pericardial effusion treated by intrapericardial Cinobufacini injection instillation
    Sun, Tao
    Zhang, Yuhua
    Shen, Yang
    Hu, Kaiwen
    Zuo, Minghuan
    BIOSCIENCE TRENDS, 2014, 8 (04) : 235 - 239
  • [3] Intrapericardial Chemotherapy for The Management of Malignant Pericardial Effusion of a Metastatic Breast Cancer Patient-A Case Report
    Ugocsai, Peter
    Gerthofer, Valeria
    Weber, Florian
    Rechenmacher, Michael
    Hatzipanagiotou, Maria
    Ortmann, Olaf
    Seitz, Stephan
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 : 27 - 27
  • [4] Pericardial effusion in a patient with advanced lung cancer
    Adams, CP
    Trachy, JW
    JOURNAL OF EMERGENCY MEDICINE, 2002, 23 (04): : 409 - 411
  • [5] Advanced lung cancer presenting with malignant pericardial effusion
    Sadiq, Abid M.
    Sadiq, Adnan M.
    Nkya, Gilbert Z.
    CLINICAL CASE REPORTS, 2021, 9 (06):
  • [6] Intrapericardial cisplatin for the management of patients with large malignant pericardial effusion in the course of the lung cancer
    Tomkowski, WZ
    Filipecki, S
    LUNG CANCER, 1997, 16 (2-3) : 215 - 222
  • [7] Bevacizumab for ramucirumab refractory malignant pleural effusion in non-small cell lung cancer: a case report and review of the literature
    Mori, Ryobu
    Fujimoto, Daichi
    Ito, Munehiro
    Tomii, Keisuke
    ONCOTARGET, 2017, 8 (29) : 48521 - 48524
  • [8] INTRAPERICARDIAL MITOMYCIN-C FOR THE MANAGEMENT OF MALIGNANT PERICARDIAL-EFFUSION SECONDARY TO GASTRIC-CANCER - CASE-REPORT AND REVIEW
    KOHNOE, S
    MAEHARA, Y
    TAKAHASHI, I
    SAITO, A
    OKADA, Y
    SUGIMACHI, K
    CHEMOTHERAPY, 1994, 40 (01) : 57 - 60
  • [9] Neonatal pericardial effusion: case report and review of the literature
    Liz, Catarina Ferraz
    Domingues, Sara
    Pinho, Liliana
    Lopes, Luisa
    Carvalho, Carmen
    Magalhaes, Mariana
    Proenca, Elisa
    JOURNAL OF PEDIATRIC AND NEONATAL INDIVIDUALIZED MEDICINE, 2020, 9 (01):
  • [10] A randomised trial of intrapericardial bleomycin for malignant pericardial effusion with lung cancer (JCOG9811)
    Kunitoh, H.
    Tamura, T.
    Shibata, T.
    Imai, M.
    Nishiwaki, Y.
    Nishio, M.
    Yokoyama, A.
    Watanabe, K.
    Noda, K.
    Saijo, N.
    BRITISH JOURNAL OF CANCER, 2009, 100 (03) : 464 - 469
12345