Therapeutic Modulation of Gut Microbiota in Functional Bowel Disorders

被引：21

作者：

Lee, Hyo Jeong ^{[1
]}

Choi, Jong Kyoung ^{[2
]}

Ryu, Han Seung ^{[3
,4
]}

Choi, Chang Hwan ^{[5
]}

Kang, Eun Hee ^{[1
]}

Park, Kyung Sik ^{[6
]}

Min, Yang Won ^{[7
]}

Hong, Kyoung Sup ^{[8
,9
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Hlth Screening & Promot Ctr, Seoul, South Korea

[2] Natl Med Ctr, Dept Internal Med, Seoul, South Korea

[3] Wonkwang Univ, Coll Med, Dept Internal Med, Iksan, South Korea

[4] Digest Dis Res Inst, Iksan, South Korea

[5] Chung Ang Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[6] Keimyung Univ, Sch Med, Dept Internal Med, Daegu, South Korea

[7] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med, 81 Irwon Ro, Seoul 06351, South Korea

[8] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[9] Seoul Natl Univ, Coll Med, Liver Res Inst, Seoul, South Korea

来源：

JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY | 2017年 / 23卷 / 01期

关键词：

Diet; Fecal microbiota transplantation; Irritable bowel syndrome; Microbiota; Probiotics; CLOSTRIDIUM-DIFFICILE INFECTION; INTESTINAL BACTERIAL OVERGROWTH; RANDOMIZED CONTROLLED-TRIAL; PROBIOTIC FERMENTED MILK; DOUBLE-BLIND; FECAL MICROBIOTA; GASTROINTESTINAL SYMPTOMS; CLINICAL-TRIAL; ESCHERICHIA-COLI; GAS-PRODUCTION;

D O I：

10.5056/jnm16124

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Functional bowel disorders (FBDs) are functional gastrointestinal disorders with symptoms attributable to the middle or lower gastrointestinal tract. These include irritable bowel syndrome, functional bloating, functional. constipation, functional diarrhea, and unspecified FBD. Increasing evidence has emerged of late that intestinal microbiota is involved in the pathogenesis of FBDs. In this review, the therapeutic benefits and future perspectives of the currently available strategies for modifying the gut microbiota in FBDs are described, focusing primarily on irritable bowel syndrome and functional constipation.

引用

页码：9 / 19

页数：11

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