Synthesis of 2,3-disubstituted-1,4-naphthoquinone

被引:0
|
作者
Zhang, Sheng-Ling [1 ]
Huang, Zhi-Shu [2 ]
Gu, Lian-Quan [2 ]
机构
[1] Shaoguan Coll, Dept Chem, Shaoguan 512005, Peoples R China
[2] Zhongshan Univ, Sch Pharmaceut Sci, Guangzhou 510275, Guangdong, Peoples R China
关键词
4-hydroxycoumarin; 1,4-naphthoquinone; Michael addition;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Six 2,3-disubstituted-1,4-naphthoquinones were synthesized by the Michael addition of 4-hydroxycoumarins to 1,4-naphthoquinone in aqueous acetone (V : V = 1 : 1) at room temperature. The structures of these compounds were determined by MS, H-1 NMR spectra and elemental analysis.
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收藏
页码:1467 / 1470
页数:4
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共 16 条
  • [1] BHALERAO UT, 1989, SYNTHETIC COMMUN, P1303
  • [2] EFFECT OF THE ORAL ANTICOAGULANT, WARFARIN, ON HIV-1 REPLICATION AND SPREAD
    BOURINBAIAR, AS
    TAN, X
    NAGORNY, R
    [J]. AIDS, 1993, 7 (01) : 129 - 130
  • [3] BUGGLE K, 1973, CHEM IND-LONDON, P88
  • [4] Campbell HA, 1941, J BIOL CHEM, V138, P21
  • [5] Electrochemical study of 3,4-dihydroxybenzoic acid and 4-tert-butylcatechol in the presence of 4-hydroxycoumarin - Application to the electro-organic synthesis of coumestan derivatives
    Golabi, SM
    Nematollahi, D
    [J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1997, 430 (1-2): : 141 - 146
  • [6] Jiang H, 2004, CHINESE J ORG CHEM, V24, P1458
  • [7] Jiang H, 2006, CHINESE J ORG CHEM, V26, P715
  • [8] Structure-activity relationship in two series of aminoalkyl substituted coumarin inhibitors of gyrase B
    Laurin, P
    Ferroud, D
    Schio, L
    Klich, M
    Dupuis-Hamelin, C
    Mauvais, P
    Lassaigne, P
    Bonnefoy, A
    Musicki, B
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (19) : 2875 - 2880
  • [9] Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B
    Laurin, P
    Ferroud, D
    Klich, M
    Dupuis-Hamelin, C
    Mauvais, P
    Lassaigne, P
    Bonnefoy, A
    Musicki, B
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (14) : 2079 - 2084
  • [10] NEW SYNTHESIS OF 4-HYDROXYCOUMARINS
    SHAH, VR
    BOSE, JL
    SHAH, RC
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (04): : 677 - 678