In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B

被引：0
|
作者：
Abu Ajaj, Khalid
Graeser, Ralph
Fichtner, Iduna
Kratz, Felix
机构：
[1] Tumor Biol Ctr, Freiburg, Germany
[2] Proqinase GmbH, Freiburg, Germany
[3] Max Delbr Fcck Ctr, Berlin, Germany
来源：
CANCER RESEARCH | 2009年 / 69卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3686
引用
收藏
页数：1
相关论文
共 50 条
  • [1] In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B
    Abu Ajaj, Khalid
    Graeser, Ralph
    Fichtner, Iduna
    Kratz, Felix
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2009, 64 (02) : 413 - 418
  • [2] In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B
    Khalid Abu Ajaj
    Ralph Graeser
    Iduna Fichtner
    Felix Kratz
    Cancer Chemotherapy and Pharmacology, 2009, 64
  • [3] Optimization of an Albumin-Binding Prodrug of Doxorubicin That Is Cleaved by Prostate-Specific Antigen
    Elsadek, Bakheet
    Graeser, Ralph
    Warnecke, Andre
    Unger, Clemens
    Saleem, Tahia
    El-Melegy, Nagla
    Madkor, Hafez
    Kratz, Felix
    ACS MEDICINAL CHEMISTRY LETTERS, 2010, 1 (05): : 234 - 238
  • [4] Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B
    Warnecke, Andre
    Fichtner, Iduna
    Sass, Gretel
    Kratz, Felix
    ARCHIV DER PHARMAZIE, 2007, 340 (08) : 389 - 395
  • [5] Synthesis and in vitro evaluation of an optimized albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA)
    Elsadek, Bakheet
    Warnecke, Andre
    Kratz, Felix
    CANCER RESEARCH, 2009, 69
  • [6] Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin
    Abu Ajaj, Khalid
    Graeser, Ralph
    Kratz, Felix
    BREAST CANCER RESEARCH AND TREATMENT, 2012, 134 (01) : 117 - 129
  • [7] Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin
    Khalid Abu Ajaj
    Ralph Graeser
    Felix Kratz
    Breast Cancer Research and Treatment, 2012, 134 : 117 - 129
  • [8] Cathepsin B-Overexpressed Tumor Cell Activatable Albumin-Binding Doxorubicin Prodrug for Cancer-Targeted Therapy
    Cho, Hanhee
    Shim, Man Kyu
    Yang, Suah
    Song, Sukyung
    Moon, Yujeong
    Kim, Jinseong
    Byun, Youngro
    Ahn, Cheol-Hee
    Kim, Kwangmeyung
    PHARMACEUTICS, 2022, 14 (01)
  • [9] Combination therapy of an acid-sensitive albumin-binding prodrug of doxorubicin (INNO-206) and an albumin binding prodrug of methotrexate (AW054) that is cleaved by cathepsin B and plasmin induces complete remissions against pancreatic cancer in vivo (MiaPaca-2)
    Kratz, Felix
    Azab, Samar S. E. E. A.
    Zeisig, Rainer
    Fichtner, Iduna
    Warnecke, Andre
    CANCER RESEARCH, 2012, 72
  • [10] Albumin-binding prodrugs of camptothecin and doxorubicin with an ala-leu-ala-leu-linker that are cleaved by cathepsin B: Synthesis and antitumor efficacy
    Schmid, Bjoern
    Chung, Da-Eun
    Warnecke, Andre
    Fichtner, Iduna
    Kratz, Felix
    BIOCONJUGATE CHEMISTRY, 2007, 18 (03) : 702 - 716
12345