Statistical modeling and EM clustering of white matter fiber tracts

被引:0
|
作者
Maddah, Mahnaz [1 ]
Grimson, W. Eric L. [1 ]
Warfield, Simon K. [1 ,2 ,3 ]
机构
[1] MIT, Comp Sci & Artificial Intelligence Lab, Cambridge, MA 02139 USA
[2] Brigham & Womens Hosp, Computat Radiol Lab, 75 Francis St, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Childrens Hosp, Harvard Med Sch, Boston, MA 02115 USA
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中图分类号
TB8 [摄影技术];
学科分类号
0804 ;
摘要
A statistical model of the fiber bundles is calculated as the average and standard deviation of a parametric representation of the fiber tracts, using the coefficients of the 3D quintic B-spline representation of the tracts. An atlas of the fiber tracts is constructed by averaging the bundle models over a population with the fiber tracts mapped onto the atlas coordinate. Using the model representation and with the atlas as the prior map, expectation-maximization (EM) is performed to cluster the fiber tracts in a mixture model framework. As an application, the method is applied to cluster the corpus callosum fiber tracts into its subdivisions and to calculate quantitative parameters for each region.
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页码:53 / +
页数:2
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