HUMAN PLASMA TOXICITY IN DIFFERENTIATED HepaRG PROGENITOR CELLS IN THE CONTEXT OF THE BIOARTIFICIAL LIVER

被引：0
|
作者：
Van Wenum, M. [1 ,2 ]
Chamuleau, R. A. F. M. [2 ]
Hendriks, E. J. [1 ]
van Gulik, T. M. [1 ]
Hoekstra, R. [1 ,2 ]
机构：
[1] Univ Amsterdam, Surg Lab, Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Tytgat Inst Liver & Intestinal Res, NL-1105 AZ Amsterdam, Netherlands
来源：
JOURNAL OF HEPATOLOGY | 2015年 / 62卷
关键词：
D O I：
10.1016/S0168-8278(15)30297-X
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
P1303
引用
收藏
页码：S328 / S328
页数：1
相关论文
共 50 条
  • [1] EFFECTS OF HEALTHY- AND ACUTE LIVER FAILURE PLASMA ON DIFFERENTIATED HUMAN HEPARG PROGENITOR CELLS IN MONOLAYERS AND BIOARTIFICIAL LIVERS
    Van Wenum, M.
    Chamuleau, R.
    Jongejan, A.
    Treskes, P.
    Meisner, S.
    Hendriks, E.
    van Gulik, T.
    Moerland, P.
    Hoekstra, R.
    [J]. JOURNAL OF HEPATOLOGY, 2016, 64 : S308 - S308
  • [2] Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure
    Nibourg, Geert A. A.
    Chamuleau, Robert A. F. M.
    van der Hoeven, Tessa V.
    Maas, Martinus A. W.
    Ruiter, An F. C.
    Lamers, Wouter H.
    Elferink, Ronald P. J. Oude
    van Gulik, Thomas M.
    Hoekstra, Ruurdtje
    [J]. PLOS ONE, 2012, 7 (06):
  • [3] The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics
    Guillouzo, Andre
    Corlu, Anne
    Aninat, Caroline
    Glaise, Denise
    Morel, Fabrice
    Guguen-Guillouzo, Christiane
    [J]. CHEMICO-BIOLOGICAL INTERACTIONS, 2007, 168 (01) : 66 - 73
  • [4] HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity
    van Wenum, Martien
    Treskes, Philipp
    Adam, Aziza A. A.
    van der Mark, Vincent. A.
    Jongejan, Aldo
    Moerland, Perry D.
    van Gulik, Thomas M.
    Elferink, Ronald P. J. Oude
    Chamuleau, Robert A. F. M.
    Hoekstra, Ruurdtje
    [J]. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 48 (05) : 2189 - 2204
  • [5] Scaling-up of a HepaRG progenitor cell based bioartificial liver: optimization for clinical application and transport
    van Wenum, Martien
    Treskes, Philipp
    Tang, Chung-Yin
    Coppens, Esmee J.
    Jansen, Koen
    Hendriks, Erik J.
    Camus, Sandrine
    van Gulik, Thomas M.
    Chamuleau, Robert A. F. M.
    Hoekstra, Ruurdtje
    [J]. BIOFABRICATION, 2017, 9 (03)
  • [6] Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-Bioartificial Liver
    Nibourg, Geert A. A.
    Hoekstra, Ruurdtje
    van der Hoeven, Tessa V.
    Ackermans, Mariette T.
    Hakvoort, Theodorus B. M.
    van Gulik, Thomas M.
    Chamuleau, Robert A. F. M.
    [J]. LIVER INTERNATIONAL, 2013, 33 (04) : 516 - 524
  • [7] Hepatocyte-Like Cells Differentiated from Human iPS: Relevance to a Bioartificial Liver.
    Yu, Yue
    Liu, Hongling
    Amiot, Bruce
    Ikeda, Yasuhiro
    Duncan, Stephen
    Nyberg, Scott Lilly
    [J]. LIVER TRANSPLANTATION, 2012, 18 : S146 - S146
  • [8] Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix
    Kanninen, Liisa K.
    Porola, Pauliina
    Niklander, Johanna
    Malinen, Melina M.
    Corlu, Anne
    Guguen-Guillouzo, Christiane
    Urtti, Arto
    Yliperttula, Marjo L.
    Lou, Yan-Ru
    [J]. EXPERIMENTAL CELL RESEARCH, 2016, 341 (02) : 207 - 217
  • [9] The human hepatoma heparg cells: A new in vitro model for xenobiotic metabolism and toxicity studies in human liver
    Aninat, Caroline
    Glaise, Denise
    Levee, Marc
    Chesne, Christophe
    Morel, Fabrice
    Fardel, Olivier
    Guguen-Guillouzo, Christiane
    Guillouzo, Andre
    [J]. DRUG METABOLISM REVIEWS, 2006, 38 : 152 - 153
  • [10] Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells
    Le Vee, Marc
    Noel, Gregory
    Jouan, Elodie
    Stieger, Bruno
    Fardel, Olivier
    [J]. TOXICOLOGY IN VITRO, 2013, 27 (06) : 1979 - 1986
12345