Comparison of tumor markers in patients with squamous cell carcinoma of the head and neck

被引:0
|
作者
Ogawa, T
Tsurusako, Y
Kimura, N
Nishioka, S
Akagi, H
Nishizaki, K
Nishioka, K
Rutka, J
机构
[1] Okayama Univ, Sch Med, Dept Otolaryngol, Okayama 7008558, Japan
[2] Takinomiya Sougou Hosp, Kagawa, Japan
[3] Univ Toronto, Toronto Hosp, Toronto, ON, Canada
关键词
carcinoembryonic antigen; Cyfra; 21-1; squamous cell carcinoma antigen;
D O I
暂无
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The serum concentrations of three separate tumor markers, squamous cell carcinoma antigen (SCC Ag), carcinoembryonic antigen (CEA) and Cyfra 21-1 were clinically correlated in 86 randomly selected patients with squamous cell carcinoma involving the head and neck. Positive findings for each tumor marker were totalled and statistically analysed. The upper limits of normal for SCC Ag, CEA and Cyfra 21-1 were set at 1.5, 2.5 and 2.0 ng/ml, respectively. Positivity rates were 20.6% for SCC Ag, 14.0% for CEA and 41.7% for Cyfra 21-1. Elevated Cyfra 21-1 concentrations correlated somewhat with age, whereas elevated CEA levels correlated with the site of tumor involvement. Overall, Cyfra 21-1 appeared to be the most useful marker in head and neck squamous cell carcinoma.
引用
收藏
页码:72 / 76
页数:5
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