Clinical management of thrombophilia-related placental vascular complications

被引:42
|
作者
Brenner, B [1 ]
机构
[1] Rambam Med Ctr, Dept Hematol & Bone Marrow Transplantat, Thrombosis & Hemostatsis Unit, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
关键词
D O I
10.1182/blood-2003-08-2744
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pregnancy is a hypercoagulable state with an increased thrombotic risk throughout gestation and the postpartum period. Women with thrombophilia may have a further increased risk of placental vascular complications, including pregnancy loss, preeciampsia, intrauterine growth restriction, and placental abruption. Preliminary data suggest that maternal antithrombotic prophylaxis may result in improved gestational outcome. Randomized trials are under way and hopefully will optimize maternal and neonatal outcome. (C) 2004 by The American Society of Hematology
引用
收藏
页码:4003 / 4009
页数:7
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