Surgical experimentation and clinical trials: differences and related ethical problems

被引:0
|
作者
Petrini, Carlo [1 ]
机构
[1] Ist Super Sanita, Unita Bioet, I-00162 Rome, Italy
来源
关键词
bioethics; human experimentation; informed consent; placebo; surgery; SHAM SURGERY; INNOVATION; CHALLENGES;
D O I
10.4415/ANN_13_02_14
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Surgical techniques are not introduced into clinical practice as the result of randomised clinical trials (RCT), but usually through the gradual evolution of existing techniques or, more rarely, through audacious departures from the norm that are decided by a surgical team on the basis of experience. Sham surgery is held by some to be not only an ethically acceptable procedure but also a perfectly fit and proper one, as it could endow surgical experiments with the strict methodological and statistical precision typically associated with RCTs. This article first briefly examines some of the methodological aspects of both RCTs and surgical experiments and then offers a few considerations regarding the ethical issues raised by sham surgery.
引用
收藏
页码:230 / 233
页数:4
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