Creating a Health Utility Value for Birdshot Chorioretinopathy

Purpose To create a health utility value for birdshot chorioretinopathy (BCR) using Time Trade-Off (TTO) and Standard Gamble (SG) utilities. Method Adult BCR patients completed TTO, SG, EQ-5D-5L, and NEI VFQ-25 questionnaires and underwent a detailed history and clinical examination. Results A total of 28 BCR patients (9 M, 19 F; mean age 62 years, range 47-83) were included. There were 22 patients with a logMAR vision of 0.3 or better in both eyes. Mean TTO was 0.90 +/- SD 0.18 (range 0.33-1.0) and mean SG was 0.94 +/- SD 0.14 (range 0.5-1.0). TTO correlated with EQ-5D-5L index value (p= .024) and NEI VFQ-25 composite score (p= .015). Conclusions Of 28 patients with BCR, 11 would trade remaining life (mean 5.4 years), and 6 would take a risk of immediate death (mean 28% risk), in return for perfect vision in both eyes for the rest of their life.