Case Report: Cutaneous Leishmaniasis in a Rheumatoid Arthritis Patient Receiving Methotrexate

被引：1
|
作者：
Amato, Valdir Sabbaga [1 ,2 ]
de Souza, Regina Maia [1 ]
Franco, Lucas Augusto Moyses [1 ,2 ]
Martins, Roberta Cristina Ruedas [1 ]
da Silva, Camila Alves Maia [1 ]
Emori, Christini Takemi [1 ,2 ]
Celeste, Beatriz Julieta [2 ,3 ]
Castanheira, Gabriel Victor [1 ,2 ]
Tuon, Felipe Francisco [3 ,4 ,5 ]
机构：
[1] Univ Sao Paulo, Inst Med Trop Sao Paulo, Lab Parasitol, Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Fac Med, Dept Molestias Infecciosas & Parasitarias, Sao Paulo, SP, Brazil
[3] Univ Sao Paulo, Lab Soroepidemiol, Inst Med Trop Sao Paulo, Sao Paulo, SP, Brazil
[4] Pontificia Univ Catol Parana, Lab Emerging Infect Dis, Curitiba, PR, Brazil
[5] Rua Imaculada Conceicao 1155, BR-80215901 Curitiba, PR, Brazil
来源：
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2022年 / 107卷 / 04期
关键词：
VISCERAL LEISHMANIASIS; VIANNIA DNA; DIAGNOSIS; BLOOD;
D O I：
10.4269/ajtmh.22-0180
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The immunosuppressive effect of methotrexate has rarely been associated with reactivation of cutaneous leishmaniasis. Here we present a case of a cutaneous leishmaniasis patient with atypical clinical symptoms without splenomegaly but with cutaneous manifestations after treatment of rheumatoid arthritis with methotrexate and blood recovery of the parasite. Next-generation sequencing was used to identify Leishmania infantum chagasi in the patient's blood sample.
引用
收藏
页码：785 / 788
页数：4
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