The Use of Retinoids in Ovarian Cancer A Review of the Literature

被引：3

作者：

Whitworth, Jenny M. ^{[1
]}

Straughn, J. Michael, Jr. ^{[1
]}

Atigadda, Venkatram R. ^{[2
]}

Muccio, Donald D. ^{[2
]}

Buchsbaum, Donald J. ^{[3
]}

机构：

[1] Univ Alabama Birmingham, Dept Obstet & Gynecol, Birmingham, AL 35233 USA

[2] Univ Alabama Birmingham, Dept Chem, Birmingham, AL 35233 USA

[3] Univ Alabama Birmingham, Dept Radiat Oncol, Birmingham, AL 35233 USA

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | 2012年 / 22卷 / 02期

关键词：

Retinoid; Ovarian cancer; RENAL-CELL CARCINOMA; PHASE-II TRIAL; LOW-DOSE ISOTRETINOIN; SERUM VITAMIN-A; CLINICAL-TRIAL; BREAST-CANCER; ANTITUMOR-ACTIVITY; FENRETINIDE METABOLITE; 13-CIS-RETINOIC ACID; SYNTHETIC RETINOIDS;

D O I：

10.1097/IGC.0b013e318236a2ec

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Ovarian cancer is the deadliest of all gynecologic malignancies. The search for novel treatment modalities to augment traditional chemotherapy and improve quality of life is ongoing. Retinoids, a class of compounds composed of vitamin A, its natural derivatives, and synthetic analogs, have been studied extensively in both the prevention and treatment of gynecologic malignancies. In this article, we reviewed preclinical studies and clinical trials conducted using retinoids in ovarian cancer.

引用

页码：191 / 198

页数：8

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