Effects of Site-specific Phosphorylation on the Structure and Functions of the Intrinsically Disordered N-terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor

被引：0
|
作者：
Kumar, Raj [1 ]
Garza, Anna S. [2 ]
Khan, Shagufta H. [1 ]
机构：
[1] Commonwealth Med Coll, Scranton, PA USA
[2] Univ Texas Med Branch, Galveston, TX 77555 USA
来源：
FASEB JOURNAL | 2010年 / 24卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 23 条
  • [1] Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor
    Garza, Anna M. S.
    Khan, Shagufta H.
    Kumar, Raj
    MOLECULAR AND CELLULAR BIOLOGY, 2010, 30 (01) : 220 - 230
  • [2] Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor
    Khan, Shagufta H.
    McLaughlin, William A.
    Kumar, Raj
    SCIENTIFIC REPORTS, 2017, 7
  • [3] Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor
    Shagufta H. Khan
    William A. McLaughlin
    Raj Kumar
    Scientific Reports, 7
  • [4] Effects of different osmolytes on the induced folding of the N-terminal activation domain (AF1) of the glucocorticold receptor
    Kumar, R.
    Serrette, J. M.
    Khan, S. H.
    Miller, A. L.
    Thompson, E. B.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2007, 465 (02) : 452 - 460
  • [5] Thermodynamic Dissection of the Intrinsically Disordered N-terminal Domain of Human Glucocorticoid Receptor
    Li, Jing
    Motlagh, Hesam N.
    Chakuroff, Carolyn
    Thompson, E. Brad
    Hilser, Vincent J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (32) : 26777 - 26787
  • [6] Functional consequences of the dynamic folding of the glucocorticoid receptor N-terminal transcription activating domain (AF1)
    Thompson, EB
    Kumar, R
    FEBS JOURNAL, 2005, 272 : 479 - 479
  • [7] Binding of the N-terminal Region of Coactivator TIF2 to theIntrinsically Disordered AF1 Domain of the Glucocorticoid Receptor Is Accompanied by Conformational Reorganizations
    Khan, Shagufta H.
    Awasthi, Smita
    Guo, Chunhua
    Goswami, Devrishi
    Ling, Jun
    Griffin, Patrick R.
    Simons, S. Stoney, Jr.
    Kumar, Raj
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (53) : 44546 - 44560
  • [8] Naturally occurring osmolyte, trehalose induces a functionally active conformation in an intrinsically disordered transactivation function domain (AF1) of the Glucocorticoid Receptor
    Khan, Shagufta H.
    Arnott, John A.
    Atamna, Hani
    Ahmad, Nihal
    Kumar, Raj
    CANCER RESEARCH, 2011, 71
  • [9] Trehalose induces functionally active conformation in the intrinsically disordered N-terminal domain of glucocorticoid receptor
    Khan, Shagufta H.
    Jasuja, Ravi
    Kumar, Raj
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 35 (10): : 2248 - 2256
  • [10] Influence of flanking sequences on signaling between the activation function AF1 and DNA-binding domain of the glucocorticoid receptor
    Kumar, R.
    Thompson, E. B.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2010, 496 (02) : 140 - 145
123