6-Mercaptopurine-induced Recurrent Acute Pancreatitis in Children With Acute Lymphoblastic Leukemia/Lymphoma

被引:7
|
作者
Halalsheh, Hadeel [1 ]
Bazzeh, Faiha [1 ]
Alkayed, Khaldoun [1 ]
Salami, Khadra [1 ]
Madanat, Faris [1 ]
机构
[1] King Hussein Canc Ctr, Dept Pediat Hematol Oncol, Amman 11941, Jordan
关键词
mercaptopurine; pancreatitis; leukemia; lymphoma; INFLAMMATORY-BOWEL-DISEASE; CROHNS-DISEASE; AZATHIOPRINE; LEUKEMIA; TOXICITY; THERAPY;
D O I
10.1097/MPH.0b013e318271c92f
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Two children with acute lymphoblastic leukemia/lymphoma developed recurrent acute pancreatitis during treatment; the etiology was presumed to be secondary to 6-mercaptopurine (6MP). Both had no further attacks after discontinuation of 6MP. Acute pancreatitis secondary to 6MP is extremely rare in acute leukemia/lymphoma although it has been reported in patients with other conditions like inflammatory bowel disease; the reason for this difference is not clearly understood.
引用
收藏
页码:470 / 472
页数:3
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