Recent advances in the aetiology of adolescent idiopathic scoliosis

被引：51
|
作者：
Cheung, Kenneth M. C. [1 ]
Wang, T. [2 ]
Qiu, G. X. [2 ]
Luk, Keith D. K. [1 ]
机构：
[1] Univ Hong Kong, Queen Mary Hosp, Dept Orthopaed & Traumatol, Hong Kong, Hong Kong, Peoples R China
[2] Peking Union Med Hosp, Dept Orthopaed Surg, Beijing, Peoples R China
来源：
INTERNATIONAL ORTHOPAEDICS | 2008年 / 32卷 / 06期
关键词：
D O I：
10.1007/s00264-007-0393-y
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
The aetiology of adolescent idiopathic scoliosis (AIS) is still unknown despite many years of research effort. Theories on AIS's aetiology have included mechanical, hormonal, metabolic, neuromuscular, growth, and genetic abnormalities. Amongst these, some factors may be epiphenomena rather than the cause itself. Other factors may even contribute to curve progression, rather than curve initiation. Current views maintain that AIS is a multifactorial disease with genetic predisposing factors [Lowe et al. in J Bone Joint Surg [Am] 82:1157-1168, 2000]. With improvements in diagnostic methods, imaging and genomics, there has been considerable recent work on aetiology. This review aims to bring readers up-to-date with the latest developments in scoliosis research.
引用
收藏
页码：729 / 734
页数：6
相关论文
共 50 条
  • [1] Recent advances in the aetiology of adolescent idiopathic scoliosis
    Kenneth M. C. Cheung
    T. Wang
    G. X. Qiu
    Keith D. K. Luk
    [J]. International Orthopaedics, 2008, 32 : 729 - 734
  • [2] Recent advances in the study of candidate genes for Adolescent Idiopathic Scoliosis
    Fendri, K.
    Patten, S.
    Zaouter, C.
    Parent, S.
    Kaufman, G.
    Labelle, H.
    Edery, P.
    Moldovan, F.
    [J]. RESEARCH INTO SPINAL DEFORMITIES 7, 2010, 158 : 3 - 7
  • [3] Current insights into the aetiology of adolescent idiopathic scoliosis
    Latalski, Michal
    Danielewicz-Bromberek, A.
    Fatyga, M.
    Latalska, M.
    Kroeber, M.
    Zwolak, P.
    [J]. ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 2017, 137 (10) : 1327 - 1333
  • [4] Current insights into the aetiology of adolescent idiopathic scoliosis
    Michal Latalski
    A. Danielewicz-Bromberek
    M. Fatyga
    M. Latalska
    M. Kröber
    P. Zwolak
    [J]. Archives of Orthopaedic and Trauma Surgery, 2017, 137 : 1327 - 1333
  • [5] Adolescent idiopathic scoliosis: Is the search for aetiology constrained by the orthosis?
    Goldberg, CJ
    Moore, DP
    Fogarty, EE
    Dowling, FE
    [J]. RESEARCH INTO SPINAL DEFORMITIES 3, 2002, 88 : 222 - 225
  • [6] Advances in scoliosis brace treatment for adolescent idiopathic scoliosis
    Shaughnessy, William J.
    [J]. ORTHOPEDIC CLINICS OF NORTH AMERICA, 2007, 38 (04) : 469 - +
  • [7] Advances in epigenetic research of adolescent idiopathic scoliosis and congenital scoliosis
    Sun, Duan
    Ding, Zihao
    Hai, Yong
    Cheng, Yunzhong
    [J]. FRONTIERS IN GENETICS, 2023, 14
  • [8] ADVANCES IN THE DIAGNOSIS AND MANAGEMENT OF ADOLESCENT IDIOPATHIC SCOLIOSIS
    WEINSTEIN, SL
    [J]. JOURNAL OF PEDIATRIC ORTHOPAEDICS, 1994, 14 (05) : 561 - 563
  • [9] Adolescent idiopathic scoliosis: evidence for intrinsic factors driving aetiology and progression
    Matthew M. P. Newton Ede
    Simon W. Jones
    [J]. International Orthopaedics, 2016, 40 : 2075 - 2080
  • [10] Adolescent idiopathic scoliosis: evidence for intrinsic factors driving aetiology and progression
    Ede, Matthew M. P. Newton
    Jones, Simon W.
    [J]. INTERNATIONAL ORTHOPAEDICS, 2016, 40 (10) : 2075 - 2080
12345