Stability of pilocarpine ophthalmic solutions

被引：2
|
作者：
Pilatti, C [1 ]
Torre, MD [1 ]
Chiale, C [1 ]
Spinetto, M [1 ]
机构：
[1] Adm Nacl Medicamentos Alimentos & Tecnol Med, Inst Nacl Medicamentos, Buenos Aires, DF, Argentina
来源：
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1999年 / 25卷 / 06期
关键词：
D O I：
10.1081/DDC-100102241
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The stability of pilocarpine and pilocarpine-timolol eyedrop preparations available on the Argentine market was studied. A high-performance liquid chromatographic method that allows the estimation of pilocarpine in the presence of degradation products was used for the study according to the preestablished design. It was found that pilocarpine solutions are stable, while pilocarpine in association with timolol shows significant degradation.
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页码：801 / 805
页数：5
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