Suzuki-Miyaura Cross-Coupling Reactions of Unactivated Alkyl Halides Catalyzed by a Nickel Pincer Complex

被引：20
|
作者：
Di Franco, Thomas [1 ]
Boutin, Nicolas [1 ]
Hu, Xile [1 ]
机构：
[1] Ecole Polytech Fed Lausanne, Lab Inorgan Synth & Catalysis, Inst Chem Sci & Engn, ISIC LSCI, CH-1015 Lausanne, Switzerland
来源：
SYNTHESIS-STUTTGART | 2013年 / 45卷 / 21期
基金：
瑞士国家科学基金会;
关键词：
cross coupling; nickel; alkyl halides; pincer complex; Suzuki-Miyaura coupling; DERIVATIVES; TOSYLATES; MULTIPLE; REAGENTS; BROMIDES; LIGAND; ARYL; PD;
D O I：
10.1055/s-0033-1338544
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A nickel(II) pincer complex, [((N2N)-N-Me)Ni-Cl], was used to catalyze alkyl-alkyl and alkyl-aryl Suzuki-Miyaura coupling reactions of unactivated alkyl halides. The coupling of 9-alkyl-9-borabicyclo[3.3.1]nonane and 9-phenyl-9-borabicyclo[3.3.1]nonane reagents with alkyl halides was achieved in modest to good yields. The reactions tolerated a variety of useful functional groups including ester, ether, furan, thioether, acetal, and Boc groups.
引用
收藏
页码：2949 / 2958
页数：10
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