Fatal course of an autochthonous hepatitis E virus infection in a patient with leukemia in Germany

被引：34
|
作者：
Pfefferle, S. [2 ]
Frickmann, H. [3 ]
Gabriel, M. [1 ]
Schmitz, N. [2 ]
Guenther, S. [1 ]
Schmidt-Chanasit, J. [1 ]
机构：
[1] Bernhard Nocht Inst Trop Med, Dept Virol, D-20359 Hamburg, Germany
[2] Asklepios Hosp St Georg, Dept Hematol Oncol & Stem Cell Transplantat, D-20099 Hamburg, Germany
[3] Bundeswehr Hosp, Bernhard Nocht Inst, Dept Trop Med, D-20359 Hamburg, Germany
来源：
INFECTION | 2012年 / 40卷 / 04期
关键词：
Hepatitis E virus; Acute hepatitis; Chronic B-cell leukemia; Fatal course; Hemodialysis; HEMODIALYSIS-PATIENTS; BLOOD-TRANSFUSION; JAPAN;
D O I：
10.1007/s15010-011-0220-7
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
An acute infection with hepatitis E virus (HEV) genotype 3 subtype c was diagnosed in a patient with chronic lymphatic B-cell leukemia 6 weeks after the infusion of donor lymphocytes. Despite intensive care the patient died 39 days after admission due to pericardial effusion that was related to acute liver failure. We suggest that diagnostic procedures for detection of HEV infection should be seriously considered for the immunocompromised patient with elevated liver enzymes in the absence of a travel history to HEV endemic countries.
引用
收藏
页码：451 / 454
页数：4
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