Cd4+ T cell matters in tumor immunity

被引：30

作者：

Velders, MP ^{[1
]}

Markiewicz, MA ^{[1
]}

Eiben, GL ^{[1
]}

Kast, WM ^{[1
]}

机构：

[1] Loyola Univ, Cardinal Bernardin Canc Ctr, Canc Immunol Program, Maywood, IL 60153 USA

来源：

INTERNATIONAL REVIEWS OF IMMUNOLOGY | 2003年 / 22卷 / 02期

关键词：

dendritic cells; suppressor T cells; T cell memory; CD4(+) T cells; tumor immunology;

D O I：

10.1080/08830180305220

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

CD4(+) T cells have been shown to be able to affect tumor growth through both direct and indirect means. In addition, a requirement has been demonstrated for CD4(+) T cells in the regulation and induction of T cell memory, and CD4(+) suppressor T cells have been identified, stressing a role for CD4(+) T cells in the induction and maintenance of antitumor immune responses. A review of the involvement of CD4(+) T cells at different stages of tumor immunity is provided, and based on these data we discuss how CD4(+) T cell response induction could be incorporated into tumor immunotherapy strategies.

引用

页码：113 / 140

页数：28

共 50 条

[1] Importance of CD4+ T helper cell responses in tumor immunity
Ossendorp, F
Toes, REM
Offringa, R
van der Burg, SH
Melief, CJM
[J]. IMMUNOLOGY LETTERS, 2000, 74 (01) : 75 - 79
[2] Unbalanced neonatal CD4+ T-cell immunity
Debock, Isabelle
Flamand, Veronique
[J]. FRONTIERS IN IMMUNOLOGY, 2014, 5
[3] CD4+ T cell immunity to Salmonella is transient in the circulation
Peres, Newton G.
Wang, Nancy
Whitney, Paul
Engel, Sven
Shreenivas, Meghanashree M.
Comerford, Ian
Hocking, Dianna M.
Erazo, Anna B.
Foerster, Irmgard
Kupz, Andreas
Gebhardt, Thomas
McColl, Shaun R.
McSorley, Stephen J.
Bedoui, Sammy
Strugnell, Richard A.
[J]. PLOS PATHOGENS, 2021, 17 (10)
[4] Autophagy in CD4+ T-cell immunity and tolerance
J D Lünemann
C Münz
[J]. Cell Death & Differentiation, 2009, 16 : 79 - 86
[5] Autophagy in CD4+ T-cell immunity and tolerance
Luenemann, J. D.
Muenz, C.
[J]. CELL DEATH AND DIFFERENTIATION, 2009, 16 (01): : 79 - 86
[6] The role of CD4+ T cell responses in antitumor immunity
Pardoll, DM
Topalian, SL
[J]. CURRENT OPINION IN IMMUNOLOGY, 1998, 10 (05) : 588 - 594
[7] ANTIVIRAL IMMUNITY Deconstructing CD4+ T cell memory
Minton, Kirsty
[J]. NATURE REVIEWS IMMUNOLOGY, 2012, 12 (09) : 619 - 619
[8] CCL5 mediates CD40-driven CD4+ T cell tumor infiltration and immunity
Huffman, Austin P.
Lin, Jeffrey H.
Kim, Samuel, I
Byrne, Katelyn T.
Vonderheide, Robert H.
[J]. JCI INSIGHT, 2020, 5 (10)
[9] Cognate CD4+ T cell licensing of dendritic cells in CD8+ T cell immunity
Smith, CM
Wilson, NS
Waithman, J
Villadangos, JA
Carbone, FR
Heath, WR
Belz, GT
[J]. NATURE IMMUNOLOGY, 2004, 5 (11) : 1143 - 1148
[10] Cognate CD4+ T cell licensing of dendritic cells in CD8+ T cell immunity
Christopher M Smith
Nicholas S Wilson
Jason Waithman
Jose A Villadangos
Francis R Carbone
William R Heath
Gabrielle T Belz
[J]. Nature Immunology, 2004, 5 : 1143 - 1148

← 1 2 3 4 5 →