Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography

被引：232
|
作者：
Goetzinger, Erich [1 ]
Pircher, Michael [1 ]
Geitzenauer, Wolfgang [2 ]
Ahlers, Christian [2 ]
Baumann, Bernhard [1 ]
Michels, Stephan [2 ,3 ]
Schmidt-Erfurth, Ursula [2 ]
Hitzenberger, Christoph K. [1 ]
机构：
[1] Med Univ Vienna, Ctr Biomed Engn & Phys, Vienna, Austria
[2] Gen Hosp, Dept Ophthalmol, Vienna, Austria
[3] Univ Zurich Hosp, Dept Ophthalmol, Zurich, Switzerland
来源：
OPTICS EXPRESS | 2008年 / 16卷 / 21期
基金：
奥地利科学基金会;
关键词：
D O I：
10.1364/OE.16.016410
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We present a new method for identifying and segmenting the retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous, intensity based segmentation algorithms, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. Two different segmentation algorithms are presented and discussed: a simpler algorithm based on retardation data, and a more sophisticated algorithm based on local variations of the polarization state calculated from averaged Stokes vector elements. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes. (c) 2008 Optical Society of America
引用
收藏
页码：16410 / 16422
页数：13
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