Application of persulfate in low-temperature atmospheric-pressure plasma jet for enhanced treatment of onychomycosis

被引：6
|
作者：
Zhang, Qunxia [1 ,2 ]
Fang, Cao [1 ,3 ]
Chen, Zhu [1 ,2 ]
Huang, Qing [1 ,2 ]
机构：
[1] Chinese Acad Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Inst Tech Biol & Agr Engn, Hefei Inst Phys Sci, Hefei 230031, Peoples R China
[2] Univ Sci & Technol China, Hefei 230026, Peoples R China
[3] Anhui Jianzhu Univ, Hefei 230601, Peoples R China
来源：
PLASMA SCIENCE & TECHNOLOGY | 2020年 / 22卷 / 02期
基金：
中国国家自然科学基金;
关键词：
low-temperature plasma (LTP); persulfate; onychomycosis; Trichophyton rubrum (T rubrum); ERGOSTEROL BIOSYNTHESIS; PHOTOCATALYTIC ACTIVITY; ORGANIC CONTAMINANTS; TRICHOPHYTON-RUBRUM; HYDROXYL RADICALS; NONTHERMAL PLASMA; ESCHERICHIA-COLI; DISCHARGE PLASMA; IN-VITRO; DEGRADATION;
D O I：
10.1088/2058-6272/ab568b
中图分类号：
O35 [流体力学]; O53 [等离子体物理学];
学科分类号：
070204 ; 080103 ; 080704 ;
摘要：
Fungal infection of human nails, or onychomycosis, affects 10% of the world's adult population, but current therapies have various drawbacks. In this work, we employed a self-made low temperature plasma (LTP) device, namely, an atmospheric-pressure plasma jet (APPJ) device to treat the nails infected with Trichophyton rubrum (T. rubrum) with the aid of persulfate solution. We found that persulfate solution had a promoting effect on plasma treatment of onychomycosis. With addition of sodium persulfate, the APPJ therapy could cure onychomycosis after several times of treatment. As such, this work has demonstrated a novel and effective approach which makes good use of LTP technique in the treatment of onychomycosis.
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页数：8
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