Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels (vol 8, pg 1160, 2022)

被引:0
|
作者
Ricciuti, B.
Wang, X.
Alessi, J., V
机构
关键词
D O I
10.1001/jamaoncol.2022.5957
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1702 / 1702
页数:1
相关论文
共 50 条
  • [1] Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels
    Ricciuti, Biagio
    Wang, Xinan
    Alessi, Joao, V
    Rizvi, Hira
    Mahadevan, Navin R.
    Li, Yvonne Y.
    Polio, Andrew
    Lindsay, James
    Umeton, Renato
    Sinha, Rileen
    Vokes, Natalie, I
    Recondo, Gonzalo
    Lamberti, Giuseppe
    Lawrence, Marissa
    Vaz, Victor R.
    Leonardi, Giulia C.
    Plodkowski, Andrew J.
    Gupta, Hersh
    Cherniack, Andrew D.
    Tolstorukov, Michael Y.
    Sharma, Bijaya
    Felt, Kristen D.
    Gainor, Justin F.
    Ravi, Arvind
    Getz, Gad
    Schalper, Kurt A.
    Henick, Brian
    Forde, Patrick
    Anagnostou, Valsamo
    Janne, Pasi A.
    Van Allen, Eliezer M.
    Nishino, Mizuki
    Sholl, Lynette M.
    Christiani, David C.
    Lin, Xihong
    Rodig, Scott J.
    Hellmann, Matthew D.
    Awad, Mark M.
    [J]. JAMA ONCOLOGY, 2022, 8 (08) : 1160 - 1168
  • [2] Increased Tumor Mutation Burden Levels and Sensitivity of Non-Small Cell Lung Cancer to PD-L1 Blockade
    Zhang, Xinmu
    Zhang, Li
    [J]. JAMA ONCOLOGY, 2023, 9 (04) : 569 - 570
  • [3] Association of a very high tumor mutational load with increased CD8+and PD-1+T-cell infiltration and improved clinical outcomes to PD-(L)1 blockade across different PD-L1 expression levels in non-small cell lung cancer.
    Ricciuti, Biagio
    Arbour, Kathryn Cecilia
    Alessi, Joao Victor Machado
    Mahadevan, Navin
    Lindsay, James
    Sinha, Rileen
    Vokes, Natalie I.
    Recondo, Gonzalo
    Lamberti, Giuseppe
    Rizvi, Hira
    Leonardi, Giulia Costanza
    Plodkowski, Andrew J.
    Felt, Kristen
    Tolstorukov, Michael
    Janne, Pasi A.
    Van Allen, Eliezer Mendel
    Sholl, Lynette M.
    Rodig, Scott J.
    Hellmann, Matthew D.
    Awad, Mark M.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [4] PD-1/PD-L1 Immune Checkpoint Blockade in Non-Small Cell Lung Cancer
    Bagley, Stephen J.
    Bauml, Joshua M.
    Langer, Corey J.
    [J]. CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2015, 13 (10) : 676 - 683
  • [5] The impact of high PD-L1 expression on the surrogate endpoints and clinical outcomes of anti-PD-1/PD-L1 antibodies in non-small cell lung cancer
    Ito, Kentaro
    Miura, Satoru
    Sakaguchi, Tadashi
    Murotani, Kenta
    Horita, Nobuyuki
    Akamatsu, Hiroaki
    Uemura, Kohei
    Morita, Satoshi
    Yamamoto, Nobuyuki
    [J]. LUNG CANCER, 2019, 128 : 113 - 119
  • [6] Plasma cell free PD-L1 RNA expression correlated with tissue PD-L1 immunohistochemical staining and tumor mutation burden in non-small cell lung cancer.
    Walker, Paul R.
    Bowling, Mark
    Sharma, Nitika
    Namireddy, Praveen
    Parent, Teresa
    Cherry, Cynthia R.
    Yeh, Chen-Hsiung
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [7] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer
    Gong, Bo
    Kiyotani, Kazuma
    Sakata, Seiji
    Nagano, Seiji
    Kumehara, Shun
    Baba, Satoko
    Besse, Benjamin
    Yanagitani, Noriko
    Friboulet, Luc
    Nishio, Makoto
    Takeuchi, Kengo
    Kawamoto, Hiroshi
    Fujita, Naoya
    Katayama, Ryohei
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2019, 216 (04): : 982 - 1000
  • [8] Association of Expression of PD-L1 with the Tumor Immune Microenvironment in Small Cell Lung Cancer
    Yu, Hui
    Badzio, Andrzej
    Boyle, Theresa A.
    Chan, Dan
    Rivard, Christopher J.
    Lu, Xian
    Kowalewski, Ashley A.
    Ellison, Kim
    Hirsch, Fred R.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S222 - S223
  • [9] The impact of genomic mutational status on PD-L1 expression and tumor mutation burden in non-small cell lung cancer
    Zhou, Qing
    Gu, Weiguang
    Fu, WenFan
    Mai, Shijie
    Lin, Daren
    Zhang, Shiyue
    Wang, Wenjing
    Zhang, Peng
    [J]. CANCER RESEARCH, 2019, 79 (13)
  • [10] Associations of the immune microenvironment with PD-L1 copy number alterations and PD-L1 expression in resected non-small cell lung cancer
    Yoshimura, Katsuhiro
    Inoue, Yusuke
    Kahyo, Tomoaki
    Kawase, Akikazu
    Tanahashi, Masayuki
    Ogawa, Hiroshi
    Inui, Naoki
    Funai, Kazuhito
    Shinmura, Kazuya
    Niwa, Hiroshi
    Suda, Takafumi
    Sugimura, Haruhiko
    [J]. CANCER RESEARCH, 2017, 77