Integrated Design Strategy for Additively Manufactured Scaffolds in Tissue Engineering

被引：0

作者：

Fucile, Pierpaolo ^{[1
]}

Russo, Teresa ^{[2
]}

De Santis, Roberto ^{[2
]}

Martorelli, Massimo ^{[3
]}

Catauro, Michelina ^{[4
]}

Gloria, Antonio ^{[2
]}

机构：

[1] Univ Naples Federico II, Dept Adv Biomed Sci, I-80131 Naples, Italy

[2] Natl Res Council Italy, Inst Polymers Composites & Biomat, Vle JF Kennedy 54,Mostra Oltremare Pad 20, I-80125 Naples, Italy

[3] Univ Naples Federico II, Dept Ind Engn, Fraunhofer JL IDEAS, Ple Tecchio 80, I-80125 Naples, Italy

[4] Univ Campania Luigi Vanvitelli, Dept Engn, Via Roma 29, I-813031 Aversa, Italy

来源：

MACROMOLECULAR SYMPOSIA | 2021年 / 395卷 / 01期

关键词：

computer‐ aided design; design for additive manufacturing; mechanical analysis; scaffold design;

D O I：

10.1002/masy.202000263

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Additive manufacturing technologies allow for the direct fabrication of 3D scaffolds with improved properties for tissue regeneration. In this scenario, design strategies and 3D fiber deposition technique are considered to develop advanced scaffolds with different lay-down patterns, tailored mechanical and biological properties. 3D poly(epsilon-caprolactone) scaffolds are manufactured and surface-modified (i.e., aminolysis). The effect of surface modification on the mechanical and biological performances of the designed 3D scaffolds is assessed.

引用

页数：3

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