Granular cell tumor of the appendix: a new case and review of the literature

被引:13
|
作者
Roncati, Luca [1 ]
Manco, Gianrocco [2 ]
Italia, Sebastiano [2 ]
Barbolini, Giuseppe [1 ]
Maiorana, Antonio [1 ]
Rossi, Aldo [2 ]
机构
[1] Univ Modena & Reggio Emilia, Dept Diagnost & Clin Med & Publ Hlth, Struttura Complessa Anat Istol & Citol Patol, Sect Pathol,Policlin Hosp, I-41125 Modena, Italy
[2] Univ Modena & Reggio Emilia, Sect Surg, Dept Emergency Med, I-41125 Modena, Italy
来源
SPRINGERPLUS | 2013年 / 2卷
关键词
Granular cell tumor; Ileocecal appendix; Chronic appendicitis; Segmented peritonitis; Oncologic management;
D O I
10.1186/2193-1801-2-649
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Granular cell tumor (GCT) is a rare and usually benign lesion of neural / schwannian origin, most frequently found in middle-age women. The appendicular involvement is extremely rare: in over half a century only twelve cases have been reported in the literature, the patients living in America and Europe. Hitherto, no cases are documented from Africa, Asia and Oceania and no cases of malignant GCTs of the appendix have been reported. Most patients were diagnosed preoperatively as having acute appendicitis, whereas in three patients the tumor was incidentally detected during major abdominal surgery. The GCTs were equally distributed between mid-appendix and tip, where lymphoid tissue is more abundant and the anatomical nerve supply is progressively reduced. Moreover, the appendix surrounding the GCTs is characterized by the presence of chronic inflammatory cells (histiocytes, plasmocytes, eosinophils, mastocytes) and, therefore, a chronic inflammation of the appendix may be an antecedent condition favouring the appearance of GCTs. The GCT of the appendix appears so to be a lesion that reflects local reactive changes in the neural / schwannian cells, rather than being a genuine neoplasm. We describe the smallest GCT of the appendix ever reported, with a detailed literature review supporting its reactive origin in the lymphatic tissue-rich sites, such as ileo cecal appendix.
引用
收藏
页码:1 / 6
页数:6
相关论文
共 50 条
  • [1] Granular cell tumor of the appendix: a case report and literature review
    Lv, Xing
    Sun, Xiaodong
    Zhou, Jianpeng
    Zhang, Yang
    Lv, Guoyue
    [J]. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2022, 50 (07)
  • [2] Granular Cell Tumor of Breast: a Case Report and Review of Literature Granular Cell Tumor of Breast: a Case Report and Review of Literature
    Rexeena, Bhargavan
    Paul, Augustine
    Nitish, Ranjan Acharya
    Kurian, Cherian
    Anila, R. K.
    [J]. INDIAN JOURNAL OF SURGICAL ONCOLOGY, 2015, 6 (04) : 446 - 448
  • [3] ENDOBRONCHIAL GRANULAR-CELL TUMOR - CYTOLOGY OF A NEW CASE AND REVIEW OF THE LITERATURE
    GLANT, MD
    WALL, RW
    RANSBURG, R
    [J]. ACTA CYTOLOGICA, 1979, 23 (06) : 477 - 482
  • [4] Metastatic granular cell tumor: A case report and review of the literature
    Aksoy, S
    Abali, H
    Kilickap, S
    Harputluoglu, H
    Erman, M
    [J]. ACTA ONCOLOGICA, 2006, 45 (01) : 91 - 94
  • [5] Granular cell tumor of stomach: A case report and review of literature
    Rosalia Patti
    Piero Luigi Almasio
    Gaetano Di Vita
    [J]. World Journal of Gastroenterology, 2006, (21) : 3442 - 3445
  • [6] Granular cell tumor of colon:Report of a case and review of literature
    Dae-KyungSohn
    Hyo-SeongChoi
    Yeon-SooChang
    Jin-MyeongHuh
    Dae-HyunKim
    Dae-YongKim
    Young-HoonKim
    Hee-JinChang
    Kyung-HaeJung
    Seung-YongJeong
    [J]. World Journal of Gastroenterology, 2004, (16) : 2452 - 2454
  • [7] Granular cell tumor of the urethra: a case report and literature review
    Pu, Chun-Xiao
    Gao, Liang
    Bai, Yun-Jin
    Han, Ping
    [J]. ASIAN JOURNAL OF ANDROLOGY, 2016, 18 (06) : 946 - 948
  • [8] Esophageal Granular Cell Tumor: A Case Report and Review of Literature
    Thumallapally, Nishitha
    Ibrahim, Uroosa
    Kesavan, Mayurathan
    Chang, Qing
    Opitz, Lynne
    Dhar, Meekoo
    Andrawes, Sherif
    [J]. CUREUS, 2016, 8 (09):
  • [9] Granular cell tumor of the esophagus: Case report and literature review
    Landesman, Nathan
    Miller, Justin
    Himes, Brent
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2008, 103 : S233 - S234
  • [10] Intraspinal granular cell tumor: a case report and review of literature
    Shen, Jun
    Wang, Sufen
    Shao, Xuefei
    Xu, Zonghua
    Dai, Yi
    Xu, Shanshui
    Mao, Jie
    Jiang, Xiaochun
    [J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2016, 9 (03): : 4013 - 4020