2012 Update: World Allergy Organization Guidelines for the assessment and management of anaphylaxis

被引:206
|
作者
Simons, F. Estelle R. [1 ,2 ]
Ardusso, Ledit R. F. [3 ]
Bilo, M. Beatrice [4 ]
Dimov, Vesselin [5 ]
Ebisawa, Motohiro [6 ]
El-Gamal, Yehia M. [7 ]
Ledford, Dennis K. [8 ]
Lockey, Richard F. [8 ]
Ring, Johannes [9 ]
Sanchez-Borges, Mario [10 ]
Senna, Gian Enrico [11 ]
Sheikh, Aziz [12 ]
Thong, Bernard Y. [13 ]
Worm, Margitta [14 ]
机构
[1] Univ Manitoba, Fac Med, Dept Pediat & Child Hlth, Winnipeg, MB, Canada
[2] Univ Manitoba, Fac Med, Dept Immunol, Winnipeg, MB R3E 0W3, Canada
[3] Univ Nacl Rosario, Catedra Neumonol Alergia & Inmunol, Fac Ciencias Med, RA-2000 Rosario, Santa Fe, Argentina
[4] Univ Hosp, Dept Allergy Immunol & Resp Dis, Ancona, Italy
[5] Univ Chicago, Sect Allergy Asthma & Immunol, Dept Pediat & Med, Chicago, IL 60637 USA
[6] Sagamihara Natl Hosp, Dept Allergy, Natl Hosp Org, Clin Res Ctr Allergy & Rheumatol, Sagamihara, Kanagawa, Japan
[7] Ain Shams Univ, Pediat Allergy & Immunol Unit, Cairo, Egypt
[8] Univ S Florida, Morsani Coll Med, Tampa, FL USA
[9] Tech Univ Muenchen, Dept Dermatol & Allergy, Munich, Germany
[10] Clin El Avila, Ctr Med Docente Trinidad, Caracas, Venezuela
[11] Verona Gen Hosp, Allergy Unit, Verona, Italy
[12] Univ Edinburgh, Ctr Populat Hlth Sci, Edinburgh, Midlothian, Scotland
[13] Tan Tock Seng Hosp, Dept Rheumatol Allergy & Immunol, Singapore, Singapore
[14] Charite, Allergie Ctr Charite, Klin Dermatol & Allergol, D-13353 Berlin, Germany
关键词
clinical diagnosis of anaphylaxis; epinephrine (adrenaline) in first-line treatment of anaphylaxis; patient risk factors for anaphylaxis; prevention of anaphylaxis; COWS MILK ALLERGY; SYSTEMIC REACTIONS; MYOCARDIAL-INFARCTION; ORAL IMMUNOTHERAPY; IGE; RISK; DIAGNOSIS; CHILDREN; DESENSITIZATION; ADRENALINE;
D O I
10.1097/ACI.0b013e328355b7e4
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Purpose of review The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis published in early 2011 provide a global perspective on patient risk factors, triggers, clinical diagnosis, treatment, and prevention of anaphylaxis. In this 2012 Update, subsequently published, clinically relevant research in these areas is reviewed. Recent findings Patient risk factors and co-factors that amplify anaphylaxis have been documented in prospective studies. The global perspective on the triggers of anaphylaxis has expanded. The clinical criteria for the diagnosis of anaphylaxis that are promulgated in the Guidelines have been validated. Some aspects of anaphylaxis treatment have been prospectively studied. Novel investigations of self-injectable epinephrine for treatment of anaphylaxis recurrences in the community have been performed. Progress has been made with regard to measurement of specific IgE to allergen components (component-resolved testing) that might help to distinguish clinical risk of future anaphylactic episodes to an allergen from asymptomatic sensitization to the allergen. New strategies for immune modulation to prevent food-induced anaphylaxis and new insights into subcutaneous immunotherapy to prevent venom-induced anaphylaxis have been described. Summary Research highlighted in this Update strengthens the evidence-based recommendations for assessment, management, and prevention of anaphylaxis made in the WAO Anaphylaxis Guidelines.
引用
收藏
页码:389 / 399
页数:11
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