Well-Ordered Mesoporous Silica Nanoparticles as a Recoverable Catalyst for One-Pot Multicomponent Synthesis of 4H-Chromene Derivatives

被引:60
|
作者
Sarrafi, Yaghoub [1 ]
Mehrasbi, Ebrahim [1 ]
Vahid, Amir [1 ]
Tajbakhsh, Mahmood [1 ]
机构
[1] Univ Mazandaran, Fac Chem, Dept Organ Chem, Babol Sar, Iran
关键词
green synthesis; multicomponent reactions; 4H-chromene derivatives; mesoporous silica nanoparticles; CONVENIENT SYNTHESIS; EFFICIENT SYNTHESIS; MCM-41; GREEN; MALONONITRILE; NANOREACTORS; ANTAGONIST; BROMIDE; LIQUID;
D O I
10.1016/S1872-2067(11)60423-3
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A simple, efficient and environmentally benign protocol for the synthesis of 4H-chromene derivatives was developed using bio-compatible, neutral, and recoverable mesoporous silica nanoparticles as a catalyst. The 4H-chromene derivatives were obtained in excellent yields by three component reaction of an aldehyde or isatin, malononitrile, and cyclic 1,3-diketones in ethanol at 60 degrees C.
引用
收藏
页码:1486 / 1494
页数:9
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