Optimized synthesis of an orthogonally protected glucosamine

被引：0

作者：

Hernández-Torres, JM ^{[1
]}

Liew, ST ^{[1
]}

Achkar, J ^{[1
]}

Wei, A ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

来源：

SYNTHESIS-STUTTGART | 2002年 / 04期

关键词：

carbohydrates; glucosamine; glycosides; orthogonal protecting groups;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Glucosamine hydrochloride was transformed into an orthogonally protected intermediate in seven steps and 34% overall yield. The synthesis includes an optimized preparation of N-phthaloyl-beta-D-glucosamine tetraacetate, a commonly used precursor in carbohydrate chemistry.

引用

页码：487 / 490

页数：4

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