Influence of non-alcoholic fatty liver disease on cardiovascular disease

被引：13

作者：

Ampuero, Javier ^{[1
]}

Romero-Gomez, Manuel ^{[1
]}

机构：

[1] Univ Seville, Hosp Univ Valme, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Unidad Gest Clin Enfermedades Digest, Seville, Spain

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2012年 / 35卷 / 08期

关键词：

Non-alcoholic fatty acid disease (NAFLD); non-alcoholic steatohepatitis (NASH); Subclinical atherosclerosis; Cardiovascular disease; Intima-media thickening; APOLIPOPROTEIN-C-III; CORONARY-ARTERY-DISEASE; INTIMA-MEDIA THICKNESS; HEPATIC STEATOSIS; INSULIN-RESISTANCE; GENE-EXPRESSION; ATHEROSCLEROSIS; RISK; POLYMORPHISM; ASSOCIATION;

D O I：

10.1016/j.gastrohep.2012.02.005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Non-alcoholic fatty liver disease encompasses a spectrum ranging from simple steatosis to steatohepatitis without excess alcohol intake and is considered to be the hepatic manifestation of metabolic syndrome. Recent studies indicate that non-alcoholic fatty liver disease is closely related to cardiovascular disease, especially to thickening of the intima-media Layer of the carotid artery, as the morphostructural manifestation of the presence of subclinical atheromatosis. Therefore, the correct management of non-alcoholic fatty liver disease would allow the natural history of both the liver disease and the atherosclerosis to be modified. (C) 2012 Elsevier Espana, S.L. and AEEH y AEG. All rights reserved.

引用

页码：585 / 593

页数：9

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