Identification and characterization of the diuretic hormone 31 receptor in the silkworm Bombyx mori

被引:8
|
作者
Iga, Masatoshi [1 ]
Kataoka, Hiroshi [1 ]
机构
[1] Univ Tokyo, Grad Sch Frontier Sci, Dept Integrated Biosci, Chiba, Japan
基金
日本学术振兴会;
关键词
diuretic hormone 31; G-protein coupled receptor; cAMP; Bombyx mori; DROSOPHILA; PEPTIDE;
D O I
10.1080/09168451.2015.1018128
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The receptor for diuretic hormone 31 (DH31R) was identified in the silkworm Bombyx mori. A heterologous expression system revealed that an orphan G-protein coupled receptor, BNGR-B1, responded to DH31 and upregulated the intracellular cAMP level. DH31R (BNGR-B1) was predominantly expressed in the anterior silk gland, midgut, and ovary, whereas DH31 was predominantly expressed in the central nervous system and midgut.
引用
收藏
页码:1305 / 1307
页数:3
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