Dust storm in the Middle East and south-west Asia is a natural hazard and the Tigris-Euphrates alluvial plain has been recognized as the main dust source in this area. In this study, more than 60 dust storms that occurred during the period 2003-2011 are investigated on the basis of MODIS satellite images, and 12 of the dust storms are selected for synoptic analysis using the NCEP-NCAR Reanalysis Data. The potential dust sources in the Middle East and south-west Asian region (20A degrees E to 80A degrees E, 5A degrees N to 50A degrees N) are analyzed and used in the synoptic analysis. Dust storms in the region can be grouped into two main categories, i.e., the Shamal dust storms and the frontal dust storms. Synoptic systems, associated with the two categories, are distinguished and the frequency of the patterns is identified. For 68% of the Shamal dust storms, a high pressure system is situated between 0A degrees E to 30A degrees E and 27A degrees N to 45A degrees N, and a low pressure system between 50A degrees E to 70A degrees E and 23A degrees N to 43A degrees N. For 86% of the frontal dust storms, a high is located between 51A degrees E to 67A degrees E and 18A degrees N to 33A degrees N and a low between 28A degrees E to 48A degrees E and 32A degrees N to 43A degrees N. Three main patterns for Shamal dust storms are identified, which represent about 60% of the Shamal dust storms. This analysis confirms that the Shamal is related to the anticyclones located over northern Africa to Eastern Europe and the monsoon trough over Iraq, southern Iran, Pakistan and the Indian Subcontinent. The analysis also shows that the main dust sink for the frontal dust storms in Tigris and Euphrates alluvial plain extends from center of Iraq to west and center of Iran and, in most severe cases, to northern Iran and the southern coast of the Caspian Sea.