The veterans affairs Saint Louis University mental status exam (slums exam) and the mini-mental status exam as predictors of mortality and institutionalization

被引:29
|
作者
Cruz-Oliver, D. M. [1 ]
Malmstrom, T. K. [2 ]
Allen, C. M. [1 ]
Tumosa, N. [1 ]
Morley, E. [1 ]
机构
[1] St Louis Univ, Sch Med, Div Geriatr Med, St Louis, MO 63104 USA
[2] St Louis Univ, Sch Med, Dept Neurol & Psychiat, St Louis, MO 63104 USA
来源
JOURNAL OF NUTRITION HEALTH & AGING | 2012年 / 16卷 / 07期
关键词
Dementia; mild cognitive impairment; SLUMS exam; MMSE; mortality; institutionalization; MILD COGNITIVE IMPAIRMENT; DETECTING DEMENTIA; AGED; 65; SURVIVAL; COMMUNITY; PEOPLE; PROGRESSION; DIAGNOSIS; COHORT; RISK;
D O I
10.1007/s12603-012-0098-9
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
To evaluate predictive validity of cognitive dysfunction of the Saint Louis University Mental Status (SLUMS) exam or Mini-Mental State Exam (MMSE) for institutionalization and mortality after 7.5-years. Longitudinal study. Geriatric Research, Education and Clinical Center Veterans Affairs Hospital St. Louis, MO. Patients (N=705) were screened for cognitive dysfunction in 2003 using the SLUMS exam and MMSE, and mortality and institutionalization up to 7.5-years later were evaluated as outcome measures. The associations between outcome measures and MMSE and SLUMS exam total scores, and cognitive status were examined using Kaplan-Meier curves and Cox proportional-hazards regression. Five hundred thirty-three charts were reviewed, 176/533(33%) patients had died and 31/526 (6%) were institutionalized during 7.5-year follow-up period. All subjects were male with a mean age of 75 years and most had high school education or greater (71%). MMSE dementia, SLUMS dementia (ps <.001) and MCI (p <.05) groups had significantly lower survival rates than normal cognition group in the Kaplan-Meier curves. Scores classified as dementia on SLUMS (HR=2.4, 95% CI 1.6-3.7; p <.001) or MMSE (HR=2.3, 95% CI 1.5-3.6; p <.001) both predicted mortality and, also, institutionalization (SLUMS: HR=3.5, 95% CI 1.3-9.1; p <.01; MMSE: HR=3.8, 95% CI 1.6-9.0; p <.001) after adjustment for covariates. Unadjusted SLUMS exam MCI predicted morality (HR=1.5, 95% CI 1.1-2.2; p <.019) but not institutionalization. The SLUMS exam and MMSE both predict mortality and institutionalization for male patients screened as positive for dementia.
引用
收藏
页码:636 / 641
页数:6
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