Discovery of novel angiogenesis inhibitors using transgenic zebrafish as a high-throughput phenotypic screening model

被引:0
|
作者
Min, Jaeki [1 ]
Kurtkaya, Serdar [1 ]
Sneed, Blossom [2 ]
Du, Yuhong [2 ]
Sandberg, Eric M. [3 ]
Baranowski, Timothy C. [3 ]
Sun, Aiming [1 ]
Snyder, James P.
Liotta, Dennis C.
Dingledine, Raymond [2 ]
机构
[1] Emory Univ, Dept Chem, Chem Biol Discovery Ctr, Atlanta, GA 30322 USA
[2] Emory Univ, Chem Biol Discovery Ctr, Dept Pharmacol, Atlanta, GA 30322 USA
[3] Zygogen LLC, Atlanta, GA 30303 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
81-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [1] High-Throughput Screening for the Discovery of Enzyme Inhibitors
    Lloyd, Matthew D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (19) : 10742 - 10772
  • [2] The Discovery of Novel Protein Tyrosine Phosphatase ε Inhibitors Using a High-throughput Screening Approach
    Yun, Hye-Yeoung
    Ku, Bonsu
    Lee, Hye Seon
    Shin, Ho-Chul
    Park, Jun-Beom
    Kim, Chang Hyen
    Kim, Seung Jun
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2017, 38 (01) : 44 - 53
  • [3] Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening
    Ostrov, David A.
    Prada, Jose A. Hernandez
    Corsino, Patrick E.
    Finton, Kathryn A.
    Le, Nhan
    Rowe, Thomas C.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (10) : 3688 - 3698
  • [4] Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms
    Qian, J
    Voorbach, MJ
    Huth, JR
    Coen, ML
    Zhang, HC
    Ng, SC
    Comess, KM
    Petros, AM
    Rosenberg, SH
    Warrior, U
    Burns, DJ
    ANALYTICAL BIOCHEMISTRY, 2004, 328 (02) : 131 - 138
  • [5] Discovery of novel Leishmania major trypanothione synthetase inhibitors by high-throughput screening
    Phan, Trong-Nhat
    Park, Kyuho Paul
    Benitez, Diego
    Comini, Marcelo A.
    Shum, David
    No, Joo Hwan
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 637 : 308 - 313
  • [6] Development of a novel high-throughput screening assay for rapid discovery of lipoxygenase inhibitors
    Deschamps, JD
    Shah, RR
    Holman, TR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U149 - U150
  • [7] Discovery of a Novel General Anesthetic Chemotype Using High-throughput Screening
    McKinstry-Wu, Andrew R.
    Bu, Weiming
    Rai, Ganesha
    Lea, Wendy A.
    Weiser, Brian P.
    Liang, David F.
    Simeonov, Anton
    Jadhav, Ajit
    Maloney, David J.
    Eckenhoff, Roderic G.
    ANESTHESIOLOGY, 2015, 122 (02) : 325 - 333
  • [8] High-throughput screening of organophosphate antidotes in a zebrafish model
    Jin, Shan
    Peterson, Randall
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
  • [9] High-throughput screening of osteosarcoma progression: A zebrafish model
    Mohseny, Alexander B.
    Xiao, Wei
    Carvalho, Ralph
    Spaink, Herman P.
    Hogendoorn, Pancras C. W.
    Cleton-Jansen, Anne-Marie
    CANCER RESEARCH, 2011, 71
  • [10] Discovery of Novel PTP1B Inhibitors by High-throughput Virtual Screening
    Debnath, Abhijit
    Rani, Anjna
    Mazumder, Rupa
    Mazumder, Avijit
    Singh, Rajesh Kumar
    Sharma, Shalini
    Srivastava, Shikha
    Chaudhary, Hema
    Mishra, Rashmi
    Khurana, Navneet
    Sanchitra, Jahanvi
    Jan, Sk Ashif
    CURRENT COMPUTER-AIDED DRUG DESIGN, 2024,