Executive Response Monitoring and Inhibitory Control in Children With Phenylketonuria: Effects of Expectancy

被引：6

作者：

Araujo, Gabriel C. ^{[1
]}

Christ, Shawn E. ^{[2
]}

Grange, Dorothy K. ^{[3
]}

Steiner, Robert D. ^{[4
,5
]}

Coleman, Carla ^{[1
]}

Timmerman, Evonne ^{[1
]}

White, Desiree A. ^{[1
]}

机构：

[1] Washington Univ, Dept Psychol, St Louis, MO 63130 USA

[2] Univ Missouri, Dept Psychol, Columbia, MO USA

[3] Washington Univ, Sch Med, St Louis Childrens Hosp, Div Genet & Genom Med,Dept Pediat, St Louis, MO 63130 USA

[4] Oregon Hlth & Sci Univ, Oregon Clin & Translat Res Inst, Doernbecher Childrens Hosp, Child Dev & Rehabil Ctr,Dept Pediat, Portland, OR 97201 USA

[5] Oregon Hlth & Sci Univ, Oregon Clin & Translat Res Inst, Doernbecher Childrens Hosp, Child Dev & Rehabil Ctr,Dept Mol & Med Genet, Portland, OR 97201 USA

来源：

DEVELOPMENTAL NEUROPSYCHOLOGY | 2013年 / 38卷 / 03期

关键词：

EARLY-TREATED PHENYLKETONURIA; ANTERIOR CINGULATE CORTEX; WHITE-MATTER; PREFRONTAL DYSFUNCTION; COGNITIVE CONTROL; ATTENTION; CONFLICT; DEFICIT; ERP; INTELLIGENCE;

D O I：

10.1080/87565641.2012.718816

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (618 years) using Go/No-Go tasks with higher (PKU n=37; control n=55) versus lower (PKU n=24; control n=25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU.

引用

页码：139 / 152

页数：14

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