Sugar expression in the mucosae of the canine uterus and vagina during the oestrous cycle and with pyometra

被引:0
|
作者
Yasunaga, Y. [1 ]
Takeuchi, T. [1 ]
Shimokawa, T. [2 ]
Asano, A. [3 ]
Nabeta, M. [4 ]
Ohta, Y. [1 ]
机构
[1] Tottori Univ, Fac Agr, Dept Lab Anim Sci, Tottori 6808553, Japan
[2] Ehime Univ, Sch Med, Dept Anat & Embryol, Toh On, Ehime 7910295, Japan
[3] Tottori Univ, Fac Agr, Dept Vet Biochem, Tottori 6808553, Japan
[4] Ehime Univ, Sch Med, Dept Obstet & Gynecol, Toh On, Ehime 7910295, Japan
来源
VETERINARY JOURNAL | 2013年 / 196卷 / 01期
关键词
Bitch; Lectins; Pyometra; Sugars; Uterus;
D O I
10.1016/j.tvjl.2012.08.008
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The pathogenesis of canine pyometra is still unclear, but bacterial infection of the endometrium, mediated by bacterial lectins, is suspected to induce pyometra. The aim of this study was to investigate sugar expression in the mucosae of the uterus and vagina of healthy dogs with normal oestrous cycles and in dogs with pyometra, using a panel of lectins to investigate the pathogenesis of pyometra. In dogs with pyometra, the uterine and vaginal mucosae were positive for lectins that selectively bind to glucose or mannose, especially during days 7-10 and 30-40 of dioestrus. These results suggest that temporal changes in sugar expression in the uterus and vagina present an opportunity for pathogens to infect the endometrium, causing pyometra. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:116 / 118
页数:3
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