Localization At The Immunological Synapse Of Adaptor Protein Grb2 and PLC Gamma-1 In Non-Stimulated Peripheral Blood T Lymphocytes From Patients With Systemic Lupus Erythematosus Suggests An In Vivo dysregulated Activation State

被引：0

作者：

Abdoel, Nursamaa ^{[1
]}

Sanchez, Mireyma ^{[1
]}

Rojas, Hector ^{[2
]}

Rodriguez, Martin ^{[1
]}

Blasini, Ana M. ^{[1
]}

机构：

[1] Hosp Univ Caracas, Caracas, Venezuela

[2] Cent Univ Venezuela, Inst Inmunol, Escuela Med, Caracas, Venezuela

来源：

ARTHRITIS AND RHEUMATISM | 2013年 / 65卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

725

引用

页码：S307 / S307

页数：1

共 5 条

[1] Altered binding to Grb2 of nucleotide exchange factors Sos and Vav in peripheral blood T lymphocytes from patients with systemic lupus erythematosus (SLE).
Cifarelli, DF
Blasini, AM
Alonso, G
Rodriguez, MA
ARTHRITIS AND RHEUMATISM, 2001, 44 (09): : S202 - S202
[2] Defective tyrosine phosphorylation, and coupling to Grb2, of the negative regulator Cbl-c in peripheral blood T lymphocytes from patients with systemic lupus erythematosus (SLE).
Cifarelli, DF
Placeres, FA
Blasini, AM
Alonso, G
Rodriguez, MA
ARTHRITIS AND RHEUMATISM, 2000, 43 (09): : S240 - S240
[3] Abnormal coupling to Grb2 in signaling through the TCR/CD3 receptor in peripheral blood T lymphocytes from patients with systemic lupus erythematosus (SLE).
Cifarelli, DF
Alonso, G
Blasini, AM
Caracas, MAR
ARTHRITIS AND RHEUMATISM, 1999, 42 (09): : S175 - S175
[4] Defective activity of ERK-1 and ERK-2 mitogen-activated protein kinases in peripheral blood T lymphocytes from patients with systemic lupus erythematosus:: potential role of altered coupling of Ras guanine nucleotide exchange factor hSos to adapter protein Grb2 in lupus T cells
Cedeño, S
Cifarelli, DF
Blasini, AM
Paris, M
Placeres, F
Alonso, G
Rodriguez, MA
CLINICAL IMMUNOLOGY, 2003, 106 (01) : 41 - 49
[5] Activation via the TCR/CD3 pathway leads to diminished mitogen activated protein kinase (MAPK) activity in peripheral blood (PB) T lymphocytes from patients with systemic lupus erythematosus (SLE).
Blasini, AM
Cedeno, S
Paris, M
Rodriguez, MA
ARTHRITIS AND RHEUMATISM, 2000, 43 (09): : S239 - S239

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