Molecular recognition and adhesion of individual DNA strands studied by dynamic force microscopy

被引：0
|
作者：
Grange, W [1 ]
Strunz, T [1 ]
Schumakovitch, I [1 ]
Güntherodt, HJ [1 ]
Hegner, M [1 ]
机构：
[1] Univ Basel, Dept Phys & Astron, Natl Ctr Competence Res Nanoscale Sci, CH-4056 Basel, Switzerland
来源：
SINGLE MOLECULES | 2001年 / 2卷 / 02期
关键词：
D O I：
10.1002/1438-5171(200107)2:2<75::AID-SIMO75>3.3.CO;2-#
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The development of versatile scanning probe methods such as atomic force microscopy (AFM) makes it today possible to study bio-adhesion on a single molecule level. In this paper, we present AFM-force-spectroscopy experiments on complementary DNA strands. From such experiments, intrinsic thermodynamical properties (energy landscape) of these weak non covalent bonds can be determined.
引用
收藏
页码：75 / 78
页数：4
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