Advanced Clinical States in Prostate Cancer

被引：20
|
作者：
Cheng, Heather H. [1 ,2 ]
Lin, Daniel W. [3 ]
Yu, Evan Y. [1 ,2 ]
机构：
[1] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98109 USA
[2] Univ Washington, Dept Med, Div Med Oncol, Seattle, WA 98109 USA
[3] Univ Washington, Dept Urol, Seattle, WA 98109 USA
来源：
UROLOGIC CLINICS OF NORTH AMERICA | 2012年 / 39卷 / 04期
关键词：
Clinical states; Prostate cancer; Androgen deprivation; Prostate-specific antigen; Castration resistant; Metastatic; ANDROGEN-DEPRIVATION THERAPY; CIRCULATING TUMOR-CELLS; MITOXANTRONE PLUS PREDNISONE; RADICAL PROSTATECTOMY; PHASE-II; BIOCHEMICAL RECURRENCE; HORMONAL-THERAPY; ANTIGEN PROGRESSION; RANDOMIZED-TRIAL; NATURAL-HISTORY;
D O I：
10.1016/j.ucl.2012.07.011
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The classification of clinical disease states within advanced prostate cancer is set apart from other solid tumors largely through measurement of prostate-specific antigen in the blood. This testing has allowed the distinction between the castration-sensitive and the castration-resistant states, to complement radiographic distinction within advanced prostate cancer. This has paved the way for advances in prognostication and treatment of patients within a heterogeneous disease group. Currently used clinical classifications have limitations and continue to evolve. The authors define the current disease states and discuss implications for prognosis and treatment decisions, as well as the limitations of existing classifications and emerging discoveries.
引用
收藏
页码：561 / +
页数：12
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