Stroma, Stroma Everywhere (Far More Than You Think)

被引：16
|
作者：
Olive, Kenneth P. [1 ,2 ]
机构：
[1] Columbia Univ, Med Ctr, Dept Med, Div Digest & Liver Dis, New York, NY USA
[2] Columbia Univ, Med Ctr, Herbert Irving Comprehens Canc Ctr, Dept Pathol, New York, NY USA
来源：
CLINICAL CANCER RESEARCH | 2015年 / 21卷 / 15期
基金：
美国国家卫生研究院;
关键词：
CHEMOTHERAPY; DELIVERY; CANCER;
D O I：
10.1158/1078-0432.CCR-15-0416
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Pancreatic ductal adenocarcinomas with high stromal content are shown to have greatly reduced overall survival, consistent with previous reports that stroma may limit drug delivery. In contrast to expectations, metastatic lesions were found to harbor as much stroma as primary tumors. (C)2015 AACR.
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页码：3366 / 3368
页数：3
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