Succinyl oleanolic acid

被引：4
|
作者：
Yang, J [1 ]
Quail, JW [1 ]
Jia, ZC [1 ]
机构：
[1] QUEENS UNIV,DEPT BIOCHEM,KINGSTON,ON K7L 3N6,CANADA
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1997年 / 53卷
关键词：
D O I：
10.1107/S0108270196013923
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The title compound, 3-[(2-carboxyethyl)carbonyloxy]olean-12-en-28-oic acid, C34H52O6, was synthesized as a derivative of oleanolic acid in order to improve its solubility and bioavailability. It has been used as an anti-inflammatory and antihepatitis drug in east Asia. The present study reveals that the succinyl moiety is equatorial with respect to the six-membered ring to which it is attached. The molecules are packed in layers in the crystal.
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页码：349 / 351
页数：3
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