Ester hydrolysis by a histidine-containing cavitein

被引：4
|
作者：
Yang, Hui [1 ]
Sherman, John C. [1 ]
机构：
[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2013年 / 23卷 / 06期
基金：
加拿大自然科学与工程研究理事会;
关键词：
Ester hydrolysis; Catalytic protein; Esterase activity; PROTEIN DESIGN; CATALYSIS; MODEL;
D O I：
10.1016/j.bmcl.2013.01.063
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
We have used a template-assembled synthetic protein (TASP) to investigate catalytic function in ester hydrolysis. A histidine-containing cavitein has been found to catalyze ester hydrolysis with a rate increase of 18 times that of background. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1752 / 1753
页数：2
相关论文
共 50 条
  • [1] MECHANISM OF ENANTIOSELECTIVE ESTER CLEAVAGE BY HISTIDINE-CONTAINING DIPEPTIDES AT A MICELLAR INTERFACE
    CLEIJ, MC
    DRENTH, W
    NOLTE, RJM
    JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (12): : 3883 - 3891
  • [2] PHOSPHORYL TRANSFER BETWEEN PHOSPHORYLATED HISTIDINE-CONTAINING PROTEIN AND HISTIDINE-CONTAINING PROTEIN IS NOT AUTOCATALYTIC
    ANDERSON, JW
    WAYGOOD, EB
    BIOCHEMISTRY, 1993, 32 (22) : 5913 - 5916
  • [3] SYNTHESIS OF HISTIDINE-CONTAINING PEPTIDES
    CHERNYSHEV, VP
    FILIPPOV.EI
    EVSTIGNE.RP
    PREOBRAZ.NA
    ZHURNAL OBSHCHEI KHIMII, 1970, 40 (07): : 1646 - +
  • [4] SYNTHETIC HISTIDINE-CONTAINING POLYPEPTIDES AS CATALYSTS FOR THE HYDROLYSIS OF PARA-NITROPHENYL ACETATE
    KATCHALSKI, E
    FASMAN, GD
    SIMONS, E
    BLOUT, ER
    GURD, FRN
    KOLTUN, WL
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1960, 88 (02) : 361 - 365
  • [5] Adsorption of Histidine and Histidine-Containing Peptides on Au(111)
    Feyer, Vitaliy
    Plekan, Oksana
    Tsud, Nataliya
    Chab, Vladimir
    Matolin, Vladimir
    Prince, Kevin C.
    LANGMUIR, 2010, 26 (11) : 8606 - 8613
  • [6] Metalloporphyrin receptors for histidine-containing peptides
    Hui Liu
    Zhan-Ting Li
    ChineseChemicalLetters, 2014, 25 (05) : 659 - 662
  • [7] Hydrolysis of natural and artificial phosphoesters using zinc model compound with a histidine-containing pseudopeptide
    Ichikawa, K
    Tarnai, M
    Uddin, MK
    Nakata, K
    Sato, S
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2002, 91 (03) : 437 - 450
  • [8] HYDROLYSIS OF PARA-NITROPHENYL ESTERS BY HISTIDINE-CONTAINING LINEAR AND CYCLIC-PEPTIDES
    KODAKA, M
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1983, 56 (12) : 3857 - 3858
  • [9] Metalloporphyrin receptors for histidine-containing peptides
    Liu, Hui
    Li, Zhan-Ting
    CHINESE CHEMICAL LETTERS, 2014, 25 (05) : 659 - 662
  • [10] Histidine-Containing Radicals in the Gas Phase
    Turecek, Frantisek
    Yao, Chunxiang
    Fung, Y. M. Eva
    Hayakawa, Shigeo
    Hashimoto, Mami
    Matsubara, Hiroshi
    JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (20): : 7347 - 7366
12345