Surface plasmon resonance imaging for nucleic acid detection

被引：48
|
作者：
D'Agata, Roberta [1 ]
Spoto, Giuseppe [1 ,2 ,3 ]
机构：
[1] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy
[2] CNR, Ist Biostrutture & Bioimmagini, I-95125 Catania, Italy
[3] Ist Nazl Biostrutture & Biosistemi, I-95125 Catania, Italy
来源：
ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2013年 / 405卷 / 2-3期
关键词：
Surface plasmon resonance imaging; DNA detection; Gold nanoparticles; PCR-free; Biosensors; ULTRASENSITIVE DETECTION; SENSITIVITY-ENHANCEMENT; MICROARRAY FABRICATION; DIGITAL MICROFLUIDICS; DIFFRACTION GRATINGS; DNA MICROARRAYS; PROBE SELECTION; QUANTUM DOTS; GENOMIC DNA; THIN-FILMS;
D O I：
10.1007/s00216-012-6563-9
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Surface plasmon resonance imaging (SPRI) is a powerful tool for simple, fast and cheap nucleic acid detection. Great efforts have been made during the last decade with the aim of developing even more sensitive and specific SPRI-based methods to be used for the direct detection of DNA and RNA. Here, after a description of the fundamentals of SPRI, the state of the art of recent platform and assay developments is presented, with special attention given to advances in SPRI signal enhancement procedures.
引用
收藏
页码：573 / 584
页数：12
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