A novel p56lck-interacting protein expressed in CD8+memory cells and tumor infiltrating T cells that inhibits proximal TCR-mediated signaling

被引：0
|
作者：
Frey, Alan [1 ]
Burns, Jeremy [1 ]
Vazquez-Cintron, Edwin [1 ]
机构：
[1] NYU, Sch Med, New York, NY USA
来源：
JOURNAL OF IMMUNOLOGY | 2012年 / 188卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：1
相关论文
共 19 条
  • [1] Efficient coupling of TCR-mediated proximal signaling events to effector function in memory CD4 T cells
    Chandok, Meena R.
    Farber, Donna L.
    JOURNAL OF IMMUNOLOGY, 2006, 176 : S200 - S200
  • [2] Differential SLP-76 expression and TCR-mediated signaling in effector and memory CD4 T cells
    Hussain, SF
    Anderson, CF
    Farber, DL
    JOURNAL OF IMMUNOLOGY, 2002, 168 (04): : 1557 - 1565
  • [3] miR-20a Inhibits TCR-Mediated Signaling and Cytokine Production in Human Naive CD4+ T Cells
    Reddycherla, Amarendra V.
    Meinert, Ines
    Reinhold, Annegret
    Reinhold, Dirk
    Schraven, Burkhart
    Simeonil, Luca
    PLOS ONE, 2015, 10 (04):
  • [4] Suppression of proximal T cell receptor signaling and lytic function in CD8+ tumor-infiltrating T cells
    Monu, Ngozi
    Frey, Alan B.
    CANCER RESEARCH, 2007, 67 (23) : 11447 - 11454
  • [5] TGF-β inhibits TCR-mediated activation of P56lck/P59fyn and Zap-70 by up-regulating SHP-1 in T cells.
    Choudhry, MA
    Sir, O
    Sayeed, MM
    FASEB JOURNAL, 2000, 14 (04): : A721 - A721
  • [6] Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells
    Wang, Xiaoqian
    Simeoni, Luca
    Lindquist, Jonathan A.
    Saez-Rodriguez, Julio
    Ambach, Andreas
    Gilles, Ernst D.
    Kliche, Stefanie
    Schraven, Burkhart
    JOURNAL OF IMMUNOLOGY, 2008, 180 (10): : 6703 - 6712
  • [7] Low affinity TCR interactions of memory and naive CD4 T cells are differentially regulated by CD4-Associated p56lck.
    Metz, DP
    Bottomly, K
    FASEB JOURNAL, 2000, 14 (06): : A991 - A991
  • [8] Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms
    Presotto, Danilo
    Erdes, Efe
    Minh Ngoc Duong
    Allard, Mathilde
    Regamey, Pierre-Olivier
    Quadroni, Manfredo
    Doucey, Marie-Agnes
    Rufer, Nathalie
    Hebeisen, Michael
    FRONTIERS IN IMMUNOLOGY, 2017, 8
  • [9] TGF-β modulates the functionality of tumor-infiltrating CD8+ T cells through effects on TCR signaling and Spred1 expression
    di Bari, Maria Giovanna
    Lutsiak, M. E. Christine
    Takai, Shinji
    Mostbock, Sven
    Farsaci, Benedetto
    Semnani, Roshanak Tolouei
    Wakefield, Lalage M.
    Schlom, Jeffrey
    Sabzevari, Helen
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2009, 58 (11) : 1811 - 1820
  • [10] TGF-β modulates the functionality of tumor-infiltrating CD8+ T cells through effects on TCR signaling and Spred1 expression
    Maria Giovanna di Bari
    M. E. Christine Lutsiak
    Shinji Takai
    Sven Mostböck
    Benedetto Farsaci
    Roshanak Tolouei Semnani
    Lalage M. Wakefield
    Jeffrey Schlom
    Helen Sabzevari
    Cancer Immunology, Immunotherapy, 2009, 58 : 1809 - 1818
12