New synthetic strategies for acyclic and cyclic pyrimidinethione nucleosides and their analogues

被引:17
|
作者
Elgemeie, Galal H. [1 ]
Alkhursani, Sheikha A. [2 ]
Mohamed, Reham A. [3 ]
机构
[1] Helwan Univ, Chem Dept, Fac Sci, Cairo, Egypt
[2] Immam Abdulrahman Bin Faisal Univ, Chem Dept, Girls Coll Sci, Organ Chem, Dammam, Saudi Arabia
[3] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Cairo, Egypt
来源
关键词
Pyridinethione nucleosides; acyclic pyrimidinethione nucleosides; cyclic pyrimidinethione nucleosides; aza pyrimidinethiones; deaza pyrimidinethiones; thioglycosides; chemotherapeutic agents; NUCLEIC-ACID COMPONENTS; ANTI-HEPATOCELLULAR CARCINOMA; TRIPLEX-FORMING PROPERTIES; N-GLYCOSYLATED PYRIDINES; CHEMICAL-SYNTHESIS; TRANSFER-RNA; CONVENIENT SYNTHESIS; ANTI-HIV-1; ACTIVITY; DIRECT ROUTE; CONDENSED PYRIDINE-2(1H)-THIONES;
D O I
10.1080/15257770.2018.1498511
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pyrimidinethione nucleosides are effective compounds and have significant and pivotal effects in several fields. New synthetic strategies for many pyrimidinethione nucleosides including acyclic and cyclic derivatives have been reported.
引用
收藏
页码:12 / 87
页数:76
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