A new tremulane sesquiterpenoid from the fungus Irpex lacteus

被引：12
|
作者：
Ding, Jian-Hai [1 ,2 ]
Li, Zheng-Hui [2 ]
Feng, Tao [2 ]
Liu, Ji-Kai [2 ]
机构：
[1] Ningxia Normal Univ, Coll Chem & Chem Engn, Engn & Technol Res Ctr Liupanshan Resources, Guyuan, Peoples R China
[2] South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan, Hubei, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2019年 / 33卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Irpex lacteus; tremulane sesquiterpenoid; biological activities;
D O I：
10.1080/14786419.2018.1448816
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new tremulane sesquiterpenoid, named irlactam A (1), was isolated from cultures of the fungus Irpex lacteus. The new structure was elucidated by spectroscopic data analysis. The compound was tested for its cytotoxicities on HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells and for its inhibitory activity against isozymes of 11 beta-hydroxysteroid dehydrogenases (11 beta-HSD). [GRAPHICS] .
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页码：316 / 320
页数：5
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