Olfactory receptor, OR51E2 is a marker for innate immune cells in ulcerative colitis

被引:0
|
作者
Lee, B. J. [1 ]
Kim, N. J. [1 ]
Park, S. B. [1 ]
Koo, J. S. [1 ]
Jeen, Y. T. [1 ]
Park, J. -J. [1 ]
Joo, M. K. [1 ]
机构
[1] Korea Univ, Seoul, South Korea
来源
关键词
D O I
10.1093/ecco-jcc/jjy222.189
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
P065
引用
收藏
页码:S118 / S119
页数:2
相关论文
共 50 条
  • [1] Intracellular Allosteric Antagonist of the Olfactory Receptor OR51E2 S
    Abaffy, Tatjana
    Fu, Olivia
    Harume-Nagai, Maira
    Goldenberg, Josh M.
    Kenyon, Victor
    Kenakin, Terry
    MOLECULAR PHARMACOLOGY, 2024, 106 (01) : 21 - 32
  • [2] The olfactory G protein-coupled receptor (Olfr-78/OR51E2) modulates the intestinal response to colitis
    Kotlo, Kumar
    Anbazhagan, Arivarasu N.
    Priyamvada, Shubha
    Jayawardena, Dulari
    Kumar, Anoop
    Chen, Yang
    Xia, Yinglin
    Finn, Patricia W.
    Perkins, David L.
    Dudeja, Pradeep K.
    Layden, Brian T.
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2020, 318 (03): : C502 - C513
  • [3] Identification of ectopic olfactory receptor gene in ulcerative colitis patients and functional analysis of OR51E2 using ex vivo culture of colonic organoid in both human and mice
    Lee, B. J.
    Joo, M. K.
    Kim, H. J.
    Park, J. -J.
    Kim, J. S.
    Bak, Y. T.
    Koo, J. S.
    Jeen, Y. T.
    JOURNAL OF CROHNS & COLITIS, 2018, 12 : S98 - S98
  • [4] Identification of a Novel Small Molecule Antagonist of the Ectopic Olfactory Receptor Olfr78/OR51E2
    Scharr, Alexandra
    Chau, Julisia
    Ni, Erwin
    Chang, Andy
    FASEB JOURNAL, 2021, 35
  • [5] Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth
    Sanz, Guenhael
    Leray, Isabelle
    Grebert, Denise
    Antoine, Sharmilee
    Acquistapace, Adrien
    Muscat, Adeline
    Boukadiri, Abdelhak
    Mir, Lluis M.
    ONCOTARGET, 2017, 8 (03) : 4330 - 4341
  • [6] The olfactory receptor OR51E2 regulates prostate cancer aggressiveness and modulates STAT3 in prostate cancer cells and in xenograft tumors
    Thomsen, Mikkel Thy
    Busk, Morten
    Zhang, Dalin
    Chiu, Chun-Lung
    Zhao, Hongjuan
    Garcia-Marques, Fernando Jose
    Bermudez, Abel
    Pitteri, Sharon
    Borre, Michael
    Brooks, James D.
    Nyengaard, Jens Randel
    BMC CANCER, 2025, 25 (01)
  • [7] Dysregulation of innate immune signalling in ulcerative colitis
    Lawrance, Ian C.
    Chew, Angela C.
    Tulic, Meri K.
    Mallon, Dominic
    Radford-Smith, Graham
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2012, 27 : 22 - 23
  • [8] Machine Learning-Based Modeling of Olfactory Receptors in Their Inactive State: Human OR51E2 as a Case Study
    Alfonso-Prieto, Mercedes
    Capelli, Riccardo
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 63 (10) : 2911 - 2917
  • [9] The Role of Innate and Adaptive Immune Cells in the Pathogenesis and Development of the Inflammatory Response in Ulcerative Colitis
    Kaluzna, Aleksandra
    Olczyk, Pawel
    Komosinska-Vassev, Katarzyna
    JOURNAL OF CLINICAL MEDICINE, 2022, 11 (02)
  • [10] Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line
    Pronin, Alexey
    Slepak, Vladlen
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 296