Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response

被引：47

作者：

Lay, Margarita K. ^{[1
]}

Gonzalez, Pablo A. ^{[1
]}

Leon, Miguel A. ^{[1
]}

Cespedes, Pablo F. ^{[1
]}

Bueno, Susan M. ^{[1
,3
]}

Riedel, Claudia A. ^{[4
,5
]}

Kalergis, Alexis M. ^{[1
,2
,3
]}

机构：

[1] Pontificia Univ Catolica Chile, Millennium Inst Immunol & Immunotherapy, Dept Mol Genet & Microbiol, Fac Ciencias Biol, Santiago 8331010, Chile

[2] Pontificia Univ Catolica Chile, Fac Med, Dept Reumatol, Santiago 8331010, Chile

[3] INSERM, U1064, Nantes, France

[4] Univ Andres Bello, Fac Ciencias Biol, Dept Ciencias Biol, Millennium Inst Immunol & Immunotherapy,Lab Biol, Santiago, Chile

[5] Univ Andres Bello, Fac Med, Santiago, Chile

来源：

MICROBES AND INFECTION | 2013年 / 15卷 / 03期

关键词：

RSV; Airway epithelial cells; Entry; Replication cycle; Immune response; Thymic stromal lymphopoietin; THYMIC STROMAL LYMPHOPOIETIN; MATRIX PROTEIN; G-GLYCOPROTEIN; IN-VITRO; RNA REPLICATION; INFLUENZA-VIRUS; TRAILER REGION; MESSENGER-RNA; LIPID RAFTS; P-PROTEIN;

D O I：

10.1016/j.micinf.2012.11.012

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication and the induction of immune response to the virus, including a new role for thymic stromal lymphopoietin in RSV immunopathology. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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页码：230 / 242

页数：13

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