Group sequential monitoring of multi-armed clinical trials

被引：0
|
作者：
Geller, NL [1 ]
Proschan, MA [1 ]
Follmann, DA [1 ]
机构：
[1] NHLBI, Off Biostat Res, Rockledge Ctr 2, Bethesda, MD 20892 USA
来源：
DRUG INFORMATION JOURNAL | 1999年 / 33卷 / 02期
关键词：
group sequential monitoring; multi-armed clinical trials;
D O I：
暂无
中图分类号：
R19 [保健组织与事业（卫生事业管理）];
学科分类号：
摘要：
Monitoring of two-armed clinical trials using group sequential methods has been implemented for over 20 years. This paper considers analogous monitoring procedures for multi-armed clinical trials. Monitoring the trial based on repeated tests of a global null hypothesis, monitoring of comparisons of several treatments to a control, and monitoring of all pairwise comparisons are considered. The procedure of choice for a given situation will depend on how the application at hand is best formulated.
引用
收藏
页码：479 / 486
页数：8
相关论文
共 50 条
  • [1] Group Sequential Monitoring of Multi-Armed Clinical Trials
    Nancy L. Geller
    Michael A. Proschan
    Dean A. Follmann
    [J]. Drug information journal : DIJ / Drug Information Association, 1999, 33 (2): : 479 - 486
  • [2] Group-sequential response-adaptive designs for multi-armed trials
    Liu, Wenyu
    Coad, D. Stephen
    [J]. SEQUENTIAL ANALYSIS-DESIGN METHODS AND APPLICATIONS, 2023, 42 (02): : 112 - 128
  • [3] Simple sequential boundaries for treatment selection in multi-armed randomized clinical trials with a control
    Cheung, Ying Kuen
    [J]. BIOMETRICS, 2008, 64 (03) : 940 - 949
  • [4] On Multi-Armed Bandit Designs for Dose-Finding Clinical Trials
    Aziz, Maryam
    Kaufmann, Emilie
    Riviere, Marie-Karelle
    [J]. JOURNAL OF MACHINE LEARNING RESEARCH, 2021, 22
  • [5] On multi-armed bandit designs for dose-finding clinical trials
    Aziz, Maryam
    Kaufmann, Emilie
    Riviere, Marie-Karelle
    [J]. Journal of Machine Learning Research, 2021, 22
  • [6] Group sequential methods for monitoring multi-arm clinical trials
    Liu, Danni
    Melia, Michele
    [J]. TRIALS, 2017, 18
  • [7] Multi-armed Bandit Models for the Optimal Design of Clinical Trials: Benefits and Challenges
    Villar, Sofia S.
    Bowden, Jack
    Wason, James
    [J]. STATISTICAL SCIENCE, 2015, 30 (02) : 199 - 215
  • [8] Revisiting the multi-armed bandit model for the optimal design of clinical trials: benefits and drawbacks
    Sofia S Villar
    Jack Bowden
    James Wason
    [J]. Trials, 14 (Suppl 1)
  • [9] Multi-armed SPHINCS
    Banegas, Gustavo
    Caullery, Florian
    [J]. APPLIED CRYPTOGRAPHY AND NETWORK SECURITY WORKSHOPS, ACNS 2023 SATELLITE WORKSHOPS, ADSC 2023, AIBLOCK 2023, AIHWS 2023, AIOTS 2023, CIMSS 2023, CLOUD S&P 2023, SCI 2023, SECMT 2023, SIMLA 2023, 2023, 13907 : 500 - 514
  • [10] A response-adaptive randomization procedure for multi-armed clinical trials with normally distributed outcomes
    Williamson, S. Faye
    Villar, Sofia S.
    [J]. BIOMETRICS, 2020, 76 (01) : 197 - 209
12345